AB216409

Anti-NFkB Inducing Kinase NIK antibody

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(5 제품이 사용된 논문 )

Rabbit Polyclonal NFkB Inducing Kinase NIK antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human MAP3K14 aa 900 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

대체 명칭 보기

NIK, MAP3K14, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, HsNIK

2 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain tissue labeling NFkB Inducing Kinase NIK with ab216409 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Supplier Data

Western blot - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

10% gel

All lanes:

Western blot - Anti-NFkB Inducing Kinase NIK antibody (ab216409) at 1/200 dilution

Lane 1:

Mouse kidney lysate

Lane 2:

Mouse brain lysate

Secondary

All lanes:

Goat Anti-Rabbit IgG Antibody (H+L), HR at 1/3000 dilution

Predicted band size: 104 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human MAP3K14 aa 900 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q99558

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/100 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway (PubMed : 25406581, PubMed : 29230214). Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response (PubMed : 25406581). Could act in a receptor-selective manner.

See full target information MAP3K14

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제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in oncology 13:1168772 PubMed37251946

2023

Identification of the hub genes associated with prostate cancer tumorigenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Honghui Zhu,Qi Lin,Xiaomin Gao,Xixi Huang

Evidence-based complementary and alternative medicine : eCAM 2022:4194827 PubMed35774743

2022

Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Luo,Chen Xuan,Junxiong Cheng,Yu Xiong,Wenfu Cao

Cell death & disease 13:58 PubMed35031599

2022

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jianyang Xiang,Wahafu Alafate,Wei Wu,Yichang Wang,Xiaodong Li,Wanfu Xie,Xiaobin Bai,Ruichun Li,Maode Wang,Jia Wang

Science advances 6: PubMed33208359

2020

Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Yuting Ke,Meiqian Weng,Gaurav Chhetri,Muhammad Usman,Yan Li,Qing Yu,Yingzhuo Ding,Zejian Wang,Xiaolong Wang,Pinky Sultana,Marian DiFiglia,Xueyi Li

The American journal of pathology 190:252-269 PubMed31585070

2019

Host Lymphotoxin-β Receptor Signaling Is Crucial for Angiogenesis of Metanephric Tissue Transplanted into Lymphoid Sites.

Applications

Unspecified application

Species

Unspecified reactive species

Maria Giovanna Francipane,Bing Han,Eric Lagasse

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-NFkB Inducing Kinase NIK antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

Western blot - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (5)

Product promise