Anti-Norovirus Capsid protein VP1 antibody [NVGC-01]

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Biological function summary

Norovirus Capsid protein VP1 assembles into icosahedral particles forming the structure that encases the viral RNA. It works as part of a complex with other molecular groups to facilitate the virus’s entry into host cells by binding to histo-blood group antigens found on epithelial cells of the digestive tract. This protein’s structure allows it to adapt and evade the host immune response which plays role in the virus's infectivity.

Pathways

Norovirus Capsid protein VP1 involves in pathways related to viral replication and immune evasion. Inside the host it participates in interactions that inhibit immune signaling pathways. These interactions often involve proteins like the Golgi-associated mechanics to promote efficient assembly and release of viral particles. VP1's interaction with cellular machinery ensures ongoing propagation of the virus.