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AB237502

Anti-NRSN1/VMP antibody

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Rabbit Polyclonal NRSN1/VMP antibody. Suitable for WB, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NRSN1 aa 1-100.

대체 명칭 보기

VMP, NRSN1, Neurensin-1, Neuro-p24, Vesicular membrane protein of 24 kDa, Vesicular membrane protein p24

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-NRSN1/VMP antibody (AB237502)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-NRSN1/VMP antibody (AB237502)

HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for NRSN1/VMP (green) using ab237502 at 1/100 dilution in ICC/IF, followed by an Alexa Fluor®488 conjugated Goat Anti-Rabbit IgG (H+L).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human NRSN1 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q8IZ57

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보완 제품

Primary Antibodies

AB237811

Anti-ZNF695 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)

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Primary Antibodies

AB237623

Anti-WDFY2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-WDFY2 antibody (AB237623)

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Primary Antibodies

AB236887

Anti-TPPP2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TPPP2 antibody (AB236887)

  • 0
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Primary Antibodies

AB259972

Anti-SmarcAL1 antibody [EPR23912-44]

20ul selling size|RabMAb|Recombinant|Trial Size

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  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity greater than 95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

NRSN1/VMP also known as Neurensin-1 is a transmembrane protein with a molecular mass around 17 kDa. The protein predominantly expresses in neuronal tissues including the central and peripheral nervous systems. NRSN1 localizes to the membrane of small round vesicles where it appears to partake in vesicle trafficking due to its transmembrane nature.
Biological function summary

Neurensin-1 impacts neuronal development and function. It may be involved in synaptic plasticity and axonal transport although the exact biological functions are not fully extracted. Some studies suggest Neurensin-1 participates as part of a larger protein complex located in the neuronal growth cone thereby influencing cellular dynamics in neurons.

Pathways

Current data links Neurensin-1 to the endocytosis and nerve growth factor signaling pathways. These pathways are key to maintaining neuronal health and supporting neurogenesis. Neurensin-1 has demonstrated interactions with clathrin and dynamin essential proteins within these pathways revealing its importance in vesicle-mediated transport processes.

Neurensin-1 shows possible connections to neurodegenerative diseases such as Alzheimer's and Parkinson's. Neurensin-1 may influence these conditions through its interactions with proteins like amyloid-beta in Alzheimer's disease and alpha-synuclein in Parkinson's disease suggesting a role in pathological protein aggregation or clearance in neuronal cells.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. May play a role in memory consolidation (By similarity).
See full target information NRSN1
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 15:10111 PubMed39578459

2024

Histone lactylation mediated by Fam172a in POMC neurons regulates energy balance.

Applications

Unspecified application

Species

Unspecified reactive species

Zhuo Chen,Baocheng Wan,Hong Zhang,Lina Zhang,Rong Zhang,Lianxi Li,Yi Zhang,Cheng Hu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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