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AB235416

Anti-NS21 antibody

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Rabbit Polyclonal NS21 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ARMC9 aa 400 to C-terminus.

대체 명칭 보기

KIAA1868, ARMC9, LisH domain-containing protein ARMC9, Armadillo repeat-containing protein 9, Melanoma/melanocyte-specific tumor antigen KU-MEL-1, NS21

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NS21 antibody (AB235416)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NS21 antibody (AB235416)

Paraffin-embedded human tonsil tissue stained for NS21 using ab235416 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human ARMC9 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q7Z3E5

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보완 제품

Primary Antibodies

AB320819

Anti-UBR4/p600 antibody [EPR28593-48]

BOND RX™ Validated|20ul selling size|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UBR4/p600 antibody [EPR28593-48] (AB320819)

  • 0
  • 0
Primary Antibodies

AB23366

Anti-Methylated Lysine (di methyl , mono methyl ) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Methylated Lysine (di methyl , mono methyl ) antibody (AB23366)

  • 4
  • 8
Primary Antibodies

AB5417

Anti-Rhodopsin antibody [1D4]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rhodopsin antibody [1D4] (AB5417)

  • 5
  • 4
Primary Antibodies

AB219969

Anti-USP30 antibody [CL4438]

KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP30 antibody [CL4438] (AB219969)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

NS21 also known as nuclear receptor subfamily 2 group C member 1 functions as a zinc finger nuclear receptor. It has a molecular mass of about 50 kDa. This protein is expressed widely in diverse tissues including the liver brain and kidney. It acts as a transcription factor to regulate the expression of target genes across various systems.
Biological function summary

NS21 plays a significant role in gene expression modulation by binding to specific DNA response elements. It is not part of a known multi-protein complex but interacts with coactivators and corepressors to exert its function. Through these interactions NS21 can influence cellular processes such as metabolism differentiation and apoptosis. These activities demonstrate its importance in normal cellular homeostasis and functioning.

Pathways

NS21 participates in the steroid hormone receptor signaling and retinoic acid signaling pathways. It closely interacts with the retinoid X receptor (RXR) within these pathways to regulate gene expression. Through these pathways NS21 affects cellular processes that are critical for development and metabolism. By interacting with RXR it can influence the transcription of genes involved in several essential biological functions.

NS21 involvement has been observed in metabolic disorders and certain types of cancer. The protein has been connected to liver cancer through its regulation of metabolic pathways and interactions with proteins such as RXR. Additionally alterations in NS21 activity can lead to imbalances in metabolic processes contributing to disorders like diabetes. Changes in NS21 function or expression might link to these disease states suggesting the potential for targeted therapeutic interventions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in ciliogenesis (PubMed : 32453716). It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (PubMed : 32453716). Acts as a positive regulator of hedgehog (Hh)signaling (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity).
See full target information ARMC9
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

iScience 26:106468 PubMed37091236

2023

Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18.

Applications

Unspecified application

Species

Unspecified reactive species

Dawadschargal Dubiel,Jing Wang,Roland Hartig,Supattra Chaithongyot,Wolfgang Dubiel,Michael Naumann
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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