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AB322969

Anti-OAS2 antibody [EPR26734-27] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal OAS2 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.
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Sandwich ELISA - Anti-OAS2 antibody [EPR26734-27] - BSA and Azide free (Capture) (AB322969)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-OAS2 antibody [EPR26734-27] - BSA and Azide free (Capture) (AB322969)

Sandwich ELISA of ab322968 with the capture antibody ab322969 dilution at 2 ug/mL and detector antibody ab322970 dilution at 0.5 ug/mL.

Sandwich ELISA - Anti-OAS2 antibody [EPR26734-27] - BSA and Azide free (Capture) (AB322969)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-OAS2 antibody [EPR26734-27] - BSA and Azide free (Capture) (AB322969)

Interpolated concentration of native OAS2 was measured at different sample concentrations. Undiluted samples are as follows : stimulated HeLa cell extract (treated with 10 ng/mL IFN-alpha for 16 hours) (62.5 µg/mL) and mock unstimulated HeLa cell extract (62.5 µg/mL). The interpolated dilution factor corrected values are plotted (mean +/- SD, n=2). Sample dilutions are made in antibody diluent CP2 (ab319981). Interpolated concentrations of OAS2 in mock unstimulated HeLa cell extract were below the detectable range of the assay. Data represented here are indicative of assay working using example of biological sample. However, we do not guarantee same sensitivity level due to biological variation.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR26734-27

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Primary Antibodies

AB309215

Anti-ISG15 antibody [EPR24482-22] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-ISG15 antibody [EPR24482-22] - BSA and Azide free (Detector) (AB309215)

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Primary Antibodies

AB244802

Anti-Apolipoprotein CIII antibody [EPR1371(2)] - BSA and Azide free (Capture)

RabMAb|Recombinant

ELISA - Anti-Apolipoprotein CIII antibody [EPR1371(2)] - BSA and Azide free (Capture) (AB244802)

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  • 0
Primary Antibodies

AB272492

Anti-OAS1 antibody [EPR24824-162]

20ul selling size|RabMAb|Recombinant|KO Validated|Trial Size

Flow Cytometry (Intracellular) - Anti-OAS1 antibody [EPR24824-162] (AB272492)

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  • 0
Proteins & Peptides

AB87759

Recombinant Human OAS1 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human OAS1 protein (His tag N-Terminus) (AB87759)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab322969 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human OAS2. The recommended pair for sandwich ELISA is:

Capture: ab322969, Human OAS2 Capture Antibody (unconjugated)

Detector: ab322970, Human OAS2 Detector Antibody (unconjugated)

The reference range value is 0.31-20 ng/mL.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 - 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response (PubMed : 10464285, PubMed : 9880569). Activated by detection of double stranded RNA (dsRNA) : polymerizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation (PubMed : 10464285, PubMed : 11682059, PubMed : 9880569). Activation of RNASEL leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication (PubMed : 10464285, PubMed : 9880569). Can mediate the antiviral effect via the classical RNASEL-dependent pathway or an alternative antiviral pathway independent of RNASEL (PubMed : 21142819). In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation (PubMed : 21142819). May act as a negative regulator of lactation, stopping lactation in virally infected mammary gland lobules, thereby preventing transmission of viruses to neonates (By similarity). Non-infected lobules would not be affected, allowing efficient pup feeding during infection (By similarity).
See full target information OAS2

대체 명칭 보기

2'-5'-oligoadenylate synthase 2, (2-5')oligo(A) synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS, p69OAS / p71OAS, OAS2
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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