AB121495

Anti-ODR4/TTG1 antibody

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(3 제품이 사용된 논문 )

Rabbit Polyclonal ODR4/TTG1 antibody. Suitable for WB, ICC/IF, IHC-P and reacts with Mouse, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ODR4 aa 300-450.

대체 명칭 보기

C1orf27, TTG1, TTG1A, ODR4, Protein odr-4 homolog, hODR-4, LAG1-interacting protein, Transactivated by transforming growth factor beta protein 1

4 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ODR4/TTG1 antibody (AB121495)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ODR4/TTG1 antibody (AB121495)

ab121495 staining ODR4/TTG1 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.

Immunocytochemistry/ Immunofluorescence - Anti-ODR4/TTG1 antibody (AB121495)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-ODR4/TTG1 antibody (AB121495)

Immunofluorescent staining of Human cell line A-431 shows positivity in plasma membrane. Recommended concentration of ab121495 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Unknown

Western blot - Anti-ODR4/TTG1 antibody (AB121495)

Developed using the ECL technique

All lanes:

Western blot - Anti-ODR4/TTG1 antibody (ab121495) at 1/250 dilution

Lane 1:

RT-4 cell lysate

Lane 2:

U-251 MG cell lysate

Lane 3:

Human Plasma lysate

Lane 4:

Human Liver lysate

Lane 5:

Human Tonsil lysate

Predicted band size: 51 kDa

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Unknown

Western blot - Anti-ODR4/TTG1 antibody (AB121495)

Lane 1 : NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
Lane 2 : NBT-II cell lysate (Rat Wistar bladder tumour cells)

All lanes:

Western blot - Anti-ODR4/TTG1 antibody (ab121495)

Predicted band size: 51 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

IHC-P, ICC/IF, WB

applications

Immunogen

Recombinant Fragment Protein within Human ODR4 aa 300-450. The exact immunogen used to generate this antibody is proprietary information.

Q5SWX8

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The ODR4/TTG1 protein sometimes referred to simply as TTG1 performs an important role in cellular processes and signal transduction. ODR4/TTG1 has a molecular mass of approximately 42 kDa. This protein is typically expressed in sensory neurons and other types of cells involved in chemosensory pathways. By interacting with elements of the cellular membrane ODR4/TTG1 facilitates signal processing and communication within cells which is essential for coordinating proper cell function.

Biological function summary

The protein ODR4/TTG1 influences hair and trichome development particularly in plants like Arabidopsis as it participates in the development of structures on the plant surface. It forms part of a complex interacting with Glabra1 and Transparent Testa Glabra2 proteins to regulate organ identity and epidermal cell differentiation. This regulatory action is essential for the correct formation and spacing of trichomes which are small hair-like projections on the surface of leaves and stems critical for plant defense.

Pathways

ODR4/TTG1 integrates into the signaling and developmental pathways that guide epidermal cell fate and differentiation. The protein plays a significant role in the well-established MYB-bHLH-WD40 transcriptional complex pathway which is pivotal in the regulation of gene expression patterns necessary for trichome development. Important proteins related through these pathways include the basic helix-loop-helix (bHLH) transcription factors which coordinate with ODR4/TTG1 to determine epidermal cell outcomes.

The role of ODR4/TTG1 extends to certain plant disorders related to defective trichome patterning or root hair development which can influence the plant's ability to interact with its environment. Issues with ODR4/TTG1 function affect the plant’s surface properties impacting interactions with pests and other environmental factors. Moreover the protein connects with Glabra1 through shared regulatory pathways linking to disorders affecting surface structures and consequently plant resilience against environmental stressors.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

May play a role in the trafficking of a subset of G-protein coupled receptors.

See full target information ODR4

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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell reports 40:111168 PubMed35926457

2022

Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation.

Applications

Unspecified application

Species

Unspecified reactive species

David Millrine,Thomas Cummings,Stephen P Matthews,Joshua J Peter,Helge M Magnussen,Sven M Lange,Thomas Macartney,Frederic Lamoliatte,Axel Knebel,Yogesh Kulathu

General physiology and biophysics 40:103-114 PubMed33880997

2021

circ_LRIG3 contributes to the progression of hepatocellular carcinoma by elevating RNF38 via sponging miR-449a.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaonan Hu,Kaikai Zhou,Sujuan Cao,Huan Zhu,Kaihong Xie

Experimental and therapeutic medicine 21:333 PubMed33732306

2021

leaf extract prevents diabetic nephropathy through the suppression of tissue transglutaminase.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyan Yu,Qing Su,Jianan Geng,Hui Liu,Yumeng Liu,Jinming Liu,Yan Shi,Yinggang Zou

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-ODR4/TTG1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ODR4/TTG1 antibody (AB121495)

Immunocytochemistry/ Immunofluorescence - Anti-ODR4/TTG1 antibody (AB121495)

Western blot - Anti-ODR4/TTG1 antibody (AB121495)

Western blot - Anti-ODR4/TTG1 antibody (AB121495)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Proteins & Peptides

Cell Lines & Lysates

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (3)

Product promise