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AB243825

Anti-OPA1L antibody

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(1 리뷰)

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(1 출판물)

Rabbit Polyclonal OPAL1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human WBP1L aa 200-350.

대체 명칭 보기

C10orf26, OPA1L, WBP1L, WW domain binding protein 1-like, Outcome predictor in acute leukemia 1

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OPA1L antibody (AB243825)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OPA1L antibody (AB243825)

Formalin-fixed, paraffin-embedded human rectum tissue stained for OPA1L with ab243825 at 1/50 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-OPA1L antibody (AB243825)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-OPA1L antibody (AB243825)

PFA fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells labeling OPA1L using ab243825 at 4 μg/ml (green) in ICC/IF.

Western blot - Anti-OPA1L antibody (AB243825)
  • WB

Supplier Data

Western blot - Anti-OPA1L antibody (AB243825)

All lanes:

Western blot - Anti-OPA1L antibody (ab243825) at 0.4 µg/mL

Lane 1:

Vector only transfected HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

Lane 2:

OPA1L overexpression HEK-293T cell lysate

Predicted band size: 38 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human WBP1L aa 200-350. The exact immunogen used to generate this antibody is proprietary information.

Q9NX94

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보완 제품

Primary Antibodies

AB157457

Anti-OPA1 antibody [EPR11057(B)]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OPA1 antibody [EPR11057(B)] (AB157457)

  • 4
  • 5
Primary Antibodies

AB184247

Anti-DRP1 antibody [EPR19274]

20ul selling size|RabMAb|Recombinant

Western blot - Anti-DRP1 antibody [EPR19274] (AB184247)

  • 5
  • 5
Primary Antibodies

AB56889

Anti-Mitofusin 2 antibody [6A8]

Western blot - Anti-Mitofusin 2 antibody [6A8] (AB56889)

  • 4
  • 12
Biochemicals

AB146819

MitoPQ, mitochondria-targeted redox cycler

Chemical Structure - MitoPQ, mitochondria-targeted redox cycler (AB146819)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

OPAL1 also known as "Out at first homolog" 1 is a protein involved in cellular signaling. It has an approximate mass of 83 kDa. OPAL1 expression primarily occurs in hematopoietic tissues including bone marrow as well as in some cancer cell lines. The protein functions as a regulator in cellular communication playing a critical role in signal transduction pathways.
Biological function summary

OPAL1 contributes to processes such as hematopoietic cell differentiation and proliferation. It forms part of a protein complex that influences blood cell development indicating its importance in maintaining healthy blood cell populations. Though detailed mechanistic insights remain limited its association with signaling complexes suggests involvement in modulating gene expression and cell fate decisions.

Pathways

OPAL1 plays roles in cellular signaling pathways notably the JAK-STAT pathway where it interacts with other key molecules like STAT5. This pathway regulates many biological functions including immune response and cell growth. Additionally OPAL1 involvement in MAPK signaling highlights its relevance in cell proliferation and survival processes linking it with other critical proteins like ERK1/2.

OPAL1 has a notable connection with blood-related cancers like acute myeloid leukemia (AML) and chronic myeloid leukemia (CML). Alterations in OPAL1 expression or function can disrupt normal signaling leading to uncontrolled cell growth. OPAL1's interaction with proteins such as BCR-ABL in CML emphasizes its role in oncogenic pathways and highlights its potential as a therapeutic target in these diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information WBP1L
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of molecular histology 56:144 PubMed40285932

2025

Identification of the oncogenic role of centromere protein M in non-small cell lung cancer via CDC20/MYBL2/Wnt signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Ling Wu,Jun Li,Haoyu Wang,Xu Chang,Qinglong Kong
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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