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AB251398

Anti-PCDH11X antibody [EPR16916] - BSA and Azide free

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Rabbit Recombinant Monoclonal PCDH11X antibody. Carrier free. Suitable for WB and reacts with Mouse, Human samples. Cited in 1 publication.

대체 명칭 보기

KIAA1326, PCDH11, PCDHX, PCDH11X, Protocadherin-11 X-linked, Protocadherin-11, Protocadherin on the X chromosome, Protocadherin-S, PCDH-X

1 이미지
Western blot - Anti-PCDH11X antibody [EPR16916] - BSA and Azide free (AB251398)
  • WB

Supplier Data

Western blot - Anti-PCDH11X antibody [EPR16916] - BSA and Azide free (AB251398)

This data was developed using ab203520, the same antibody clone in a different buffer formulation.

Blocking and dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-PCDH11X antibody [EPR16916] (<a href='/ko/products/primary-antibodies/pcdh11x-antibody-epr16916-ab203520'>ab203520</a>) at 1/1000 dilution

Lane 1:

Mouse thalamus lysate at 10 µg

Lane 2:

Mouse hippocampus lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/ko/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/50000 dilution

Predicted band size: 148 kDa

Observed band size: 148 kDa

false

Exposure time: 3min

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR16916

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

제품 세부 정보

ab251398 is the carrier-free version of ab203520.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 - 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

PCDH11X also known as Protocadherin 11 X-linked is a protein encoded by the PCDH11X gene. It weighs around 170 kDa. This protein is expressed mainly in the brain with higher expression in cerebral cortices and hippocampus regions. PCDH11X belongs to the protocadherin family known for their role in cell adhesion. Mechanically it facilitates cell-cell interactions supporting neuronal connectivity and synapse formation.
Biological function summary

PCDH11X plays a critical role in neuronal development and differentiation. It engages in homophilic adhesion allowing neurons to communicate and establish complex networks. PCDH11X functions within synaptic junctions and contributes to maintaining neural circuitry. It often interacts with other protocadherins and is considered part of a larger adhesion protein complex which includes cadherins known to regulate cellular architecture.

Pathways

PCDH11X takes part in neural circuitry development and synaptic plasticity pathways. Notably it participates in the Wnt signaling pathway which is essential for neuronal patterning and connectivity. PCDH11X shares interaction with proteins such as beta-catenin which link cell adhesion molecules to the actin cytoskeleton further influencing signaling pathways related to neural morphogenesis.

PCDH11X shows relevance to neurodevelopmental disorders and mental health conditions like schizophrenia. Researchers notice alterations in PCDH11X expression linked to these conditions suggesting its importance in neuropsychiatric health. Additionally it is connected to the N-cadherin protein which also associates with cognitive disorders emphasizing its role in maintaining proper neural function.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Potential calcium-dependent cell-adhesion protein.
See full target information PCDH11X

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 12:3596 PubMed34155205

2021

ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Kenji Miki,Kohei Deguchi,Misato Nakanishi-Koakutsu,Antonio Lucena-Cacace,Shigeru Kondo,Yuya Fujiwara,Takeshi Hatani,Masako Sasaki,Yuki Naka,Chikako Okubo,Megumi Narita,Ikue Takei,Stephanie C Napier,Tsukasa Sugo,Sachiko Imaichi,Taku Monjo,Tatsuya Ando,Norihisa Tamura,Kenichi Imahashi,Tomoyuki Nishimoto,Yoshinori Yoshida
제품이 사용된 논문 모두 보기

Product promise

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