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AB74505

Anti-PEX3 antibody

1

(2 리뷰들)

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(1 출판물)

Rabbit Polyclonal PEX3 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human PEX3.
1 이미지
Western blot - Anti-PEX3 antibody (AB74505)
  • WB

Unknown

Western blot - Anti-PEX3 antibody (AB74505)

All lanes:

Western blot - Anti-PEX3 antibody (ab74505) at 1/500 dilution

Lane 1:

extracts from HeLa cells at 5 µg

Lane 2:

extracts from HeLa cells at 5 µg with immunising peptide

Predicted band size: 42 kDa

Observed band size: 42 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human PEX3. The exact immunogen used to generate this antibody is proprietary information.

P56589

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보완 제품

Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

  • 5
  • 24
Primary Antibodies

AB183885

Anti-PEX14 antibody

Immunocytochemistry/ Immunofluorescence - Anti-PEX14 antibody (AB183885)

  • 0
  • 0
Primary Antibodies

AB267351

Anti-TFEB antibody [EPR22941-6]

BOND RX™ Validated|Advanced Validation|RabMAb|Recombinant|KO Validated|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-TFEB antibody [EPR22941-6] (AB267351)

  • 5
  • 1
Primary Antibodies

AB95959

Anti-PEX19 antibody

Western blot - Anti-PEX19 antibody (AB95959)

  • 3
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

PEX3 also known as Peroxisomal biogenesis factor 3 is a protein involved in peroxisome formation. PEX3 has a known amino acid sequence that gives it a molecular mass of approximately 45 kDa. It is mainly expressed in tissues with high metabolic activity such as liver kidney and heart. As a membrane protein PEX3 is located on the peroxisomal membrane and plays a direct role in the import of proteins into the peroxisome.
Biological function summary

PEX3 is essential for the protein import machinery of peroxisomes. It acts as a receptor on the peroxisomal membrane interacting with other peroxisomal proteins including PEX19. This interaction helps in the assembly of peroxisomal membrane proteins. It is part of a larger protein complex necessary for the formation and maintenance of functional peroxisomes which are organelles responsible for various metabolic functions.

Pathways

PEX3 plays a central role in peroxisome biogenesis. It functions within the peroxisomal protein import pathway an important process for the maintenance of peroxisomes. In this context PEX3 interacts closely with PEX19 which acts as a chaperone and receptor for newly synthesized peroxisomal membrane proteins. Together PEX3 and PEX19 facilitate the import and proper localization of these proteins into the peroxisomal membrane.

Mutations or deficiencies in PEX3 can lead to peroxisome biogenesis disorders (PBDs) such as Zellweger syndrome. This severe genetic disorder affects multiple systems and results from impaired peroxisomal formation and function. PEX1 another protein involved in peroxisome biogenesis also relates to these disorders emphasizing the importance of coordinated interactions between these proteins for proper cellular function.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
See full target information PEX3

대체 명칭 보기

Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3, PEX3
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Oncology letters 25:5 PubMed36419754

2022

ZDHHC9 promotes colon tumor growth by inhibiting effector T cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaodan Chong,Lingxi Zhu,Dong Yu,Shasha Chen,Guang Wang,Qingzhuo Yu,Xianwei Ma,Jing Xu,Haitao Chen,Huazhang An
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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