AB67649
Mouse Polyclonal PLA2G4C antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PLA2G4C.
대체품
보완 제품
Primary Antibodies
AB91606
Anti-Lysophospholipase 1/LPL-I antibody [EPR3667]
20ul selling size|RabMAb|Recombinant|KO Validated
![Western blot - Anti-Lysophospholipase 1/LPL-I antibody [EPR3667] (AB91606)](https://content.abcam.com/products/images/lysophospholipase-1-lpl-i-antibody-epr3667-ab91606--western-blot-img147140.jpg)
- 5
- 1
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Calcium-independent phospholipase, lysophospholipase and O-acyltransferase involved in phospholipid remodeling with implications in endoplasmic reticulum membrane homeostasis and lipid droplet biogenesis (PubMed : 10085124, PubMed : 10358058, PubMed : 19501189, PubMed : 28336330, PubMed : 9705332). Preferentially hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids with choline and ethanolamine head groups, producing lysophospholipids that are used in deacylation-reacylation cycles (PubMed : 10085124, PubMed : 10358058, PubMed : 19501189, PubMed : 28336330, PubMed : 9705332). Transfers the sn-1 fatty acyl from one lysophospholipid molecule to the sn-2 position of another lysophospholipid to form diacyl, alkylacyl and alkenylacyl glycerophospholipids. Cleaves ester bonds but not alkyl or alkenyl ether bonds at sn-1 position of lysophospholipids (PubMed : 15944408, PubMed : 19501189). Catalyzes sn-2 fatty acyl transfer from phospholipids to the sn-2 position of 1-O-alkyl or 1-O-alkenyl lysophospholipids with lower efficiency (PubMed : 15944408, PubMed : 19501189). In response to dietary fatty acids, may play a role in the formation of nascent lipid droplets from the endoplasmic reticulum likely by regulating the phospholipid composition of these organelles (PubMed : 28336330).. (Microbial infection) May play a role in replication and assembly of human hepatitis C virus (HCV) (PubMed : 23015700, PubMed : 28336330). In response to HCV infection, promotes remodeling of host endoplasmic reticulum membranes to form organelle-like structures called membranous web, where HCV replication occur (PubMed : 23015700). Can further mediate translocation of replication complexes to lipid droplets to enable virion assembly (PubMed : 23015700, PubMed : 28336330).. (Microbial infection) May facilitate human T-lymphotropic virus type 1 (HTLV-1) infection by promoting leukotriene B4 (LTB4) biosynthesis. LTB4 acts as a chemoattractant for HTLV-1-infected CD4-positive T cells and favors cell to cell viral transmission.
대체 명칭 보기
Cytosolic phospholipase A2 gamma, cPLA2-gamma, Cytosolic lysophospholipase, Cytosolic lysophospholipid O-acyltransferase, Phospholipase A2 group IVC, PLA2G4C
제품이 사용된 논문 (1)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Biochemical and biophysical research communication 409:506-12 PubMed21600875
2011
Downregulation of cPLA2γ expression inhibits EGF-induced chemotaxis of human breast cancer cells through Akt pathway.
Applications
WB
Species
Human
Gang Tian,Xueqian Wang,Fei Zhang,Hua Geng,Wei Hou,Liwei Chen,Hua Guo,Ning Zhang
Product promise
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