JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB15555

Anti-Placental lactogen antibody, prediluted

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal CSH2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication.
2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental lactogen antibody, prediluted (AB15555)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental lactogen antibody, prediluted (AB15555)

ab15554 staining Human placenta by Immunohistochemistry (FFPE-sections).

This data was developed using the undiluted version of this antibody (ab15554).

Western blot - Anti-Placental lactogen antibody, prediluted (AB15555)
  • WB

Unknown

Western blot - Anti-Placental lactogen antibody, prediluted (AB15555)

This data was developed using the undiluted version of this antibody (ab15554).

Lane 1:

Western blot - Anti-Placental lactogen antibody (<a href='/ko/products/primary-antibodies/placental-lactogen-antibody-ab15554'>ab15554</a>) at 1/25 dilution

Lane 1:

Western blot - Anti-Placental lactogen antibody, prediluted (ab15555) at 1/25 dilution

All lanes:

Human placenta lysate

Predicted band size: 25 kDa

Observed band size: 23 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

style
left-column

대체품

Primary Antibodies

AB248818

Anti-Placental lactogen antibody [EPR8265] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental lactogen antibody [EPR8265] - BSA and Azide free (AB248818)

  • 0
  • 0
Primary Antibodies

AB137099

Anti-Placental lactogen antibody [EPR8265]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental lactogen antibody [EPR8265] (AB137099)

  • 0
  • 0

보완 제품

Primary Antibodies

AB62363

Anti-GCDFP 15 antibody [EP1582Y]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GCDFP 15 antibody [EP1582Y] (AB62363)

  • 1
  • 1
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 16
Primary Antibodies

AB74324

Anti-Human Growth Hormone antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Human Growth Hormone antibody (AB74324)

  • 5
  • 1
Primary Antibodies

AB134045

Anti-CD63 antibody [EPR5702] - Late Endosome Marker

20ul selling size|RabMAb|Recombinant|KO Validated|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD63 antibody [EPR5702] - Late Endosome Marker (AB134045)

  • 3
  • 6
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/25", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1", "IHCP-species-notes": "<p>10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at RT for 20 minutes. ab15555 shows cytoplasmic staining.</p>" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.6 Preservative: 0.1% Sodium azide Constituents: Tris buffered saline, 1% BSA
배송 시 보관 조건
Blue Ice
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Placental lactogen also known as chorionic somatomammotropin hormone is a glycoprotein hormone with a molecular mass of approximately 22 kDa. The hormone is primarily expressed in the syncytiotrophoblasts of the placenta during pregnancy. It shares structural similarities with other hormones like growth hormone and prolactin due to its polypeptide nature. Placental lactogen influences various physiological processes related to maternal and fetal development.
Biological function summary

Placental lactogen functions to modulate maternal metabolism to support fetal growth and development. It promotes changes in the maternal glucose metabolism ensuring an adequate energy supply to the fetus. This protein also stimulates mammary gland development preparing the mother for lactation. It does not form part of a larger protein complex acting independently in the biological processes it regulates.

Pathways

Researchers have found that placental lactogen plays a role in both the insulin-like growth factor (IGF) pathway and the JAK-STAT signaling pathway. It interacts with the IGF pathway to enhance nutrient uptake and fetal growth. Additionally its role in the JAK-STAT pathway ties it to immune modulation and cell proliferation. Placental lactogen is related to proteins such as the growth hormone and prolactin within these pathways due to their shared structural properties and similar mechanisms of action.

Studies have linked abnormal levels of placental lactogen to gestational diabetes mellitus and pre-eclampsia. Gestational diabetes arises when placental lactogen induces higher insulin resistance impacting maternal glucose regulation. Pre-eclampsia may involve imbalance in placental lactogen expression affecting placental vascular function. Researchers have noted interactions with proteins like leptin and insulin as these relate to glucose metabolism and vascular changes in pregnancy.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
See full target information CSH2

대체 명칭 보기

Chorionic somatomammotropin hormone 2, Choriomammotropin, Lactogen, Placental lactogen, PL, CSH2
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular sciences 24: PubMed37834175

2023

Derivation of Arbas Cashmere Goat Induced Pluripotent Stem Cells in LCDM with Trophectoderm Lineage Differentiation and Interspecies Chimeric Abilities.

Applications

Unspecified application

Species

Unspecified reactive species

Fang Liu,Jing Wang,Yongli Yue,Chen Li,Xuemin Zhang,Jinzhu Xiang,Hanning Wang,Xueling Li
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com