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AB18096

Anti-Plasma Cell antibody [SPM310], prediluted

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(1 출판물)

Mouse Monoclonal Plasma Cell antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Tissue preparation containing Plasma Cell protein.

대체 명칭 보기

Plasma B cell, Plasmocytes

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Plasma Cell antibody [SPM310], prediluted (AB18096)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Plasma Cell antibody [SPM310], prediluted (AB18096)

Human tonsil stained with ab18096.

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

SPM310

Isotype

IgG2a

Light chain 타입

kappa

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.

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대체품

Primary Antibodies

AB270730

Anti-Plasma Cell antibody [LIV3G11]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Plasma Cell antibody [LIV3G11] (AB270730)

  • 0
  • 0

보완 제품

Primary Antibodies

AB270730

Anti-Plasma Cell antibody [LIV3G11]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Plasma Cell antibody [LIV3G11] (AB270730)

  • 0
  • 0
Primary Antibodies

AB277100

Anti-ZBTB46 antibody [PCRP-ZBTB46-2B8]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZBTB46 antibody [PCRP-ZBTB46-2B8] (AB277100)

  • 0
  • 0
Primary Antibodies

AB270731

Anti-Thomsen-Friedenreich Antigen antibody [A78-G/A7]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [A78-G/A7] (AB270731)

  • 1
  • 1
Primary Antibodies

AB270732

Anti-ds DNA antibody [121-3]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [121-3] (AB270732)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1", "IHCP-species-notes": "<p></p> Perform enzymatic antigen retrieval before commencing with IHC staining protocol." } } }
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제품 세부 정보

The concentration of this prediluted antibody is 4µg/ml.
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특성 및 보관 정보

제형
Liquid
보관 버퍼
pH: 7.2 - 7.4 Preservative: 0.1% Sodium azide
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Plasma cells also referred to as antibody-producing cells are a type of differentiated B lymphocytes. These cells produce large amounts of antibodies and have a critical role in the immune response. Plasma cells are typically found in the bone marrow after they migrate from the lymphoid tissues where they undergo differentiation. Each plasma cell has unique antibodies that are specific to different antigens. Plasma cells are relatively large roughly 14-20 micrometers in diameter and they exhibit a high cytoplasmic volume due to rough endoplasmic reticulum abundance needed for antibody synthesis.
Biological function summary

Plasma cells synthesize and secrete antibodies which are important for identifying and neutralizing pathogens such as bacteria and viruses. These cells play an essential role in humoral immunity one of the main pathways of the adaptive immune system. Plasma cells are often part of multimolecular complexes due to their association with various immune components to create a coordinated immune response. The antibodies secreted by plasma cells bind to antigens marking them for destruction by other immune cells.

Pathways

Plasma cells are integral to the adaptive immune response and play a central role in the IgG and IgA isotype switching pathways. These pathways lead the change of antibody classes to target pathogens more effectively. Plasma cells interact closely with T-helper cells which release cytokines that influence plasma cell function and antibody production. This interaction ensures effective communication and response to specific antigens within the immune system.

Plasma cells are associated with multiple myeloma and Waldenström’s macroglobulinemia which are types of blood cancer. In multiple myeloma plasma cells grow uncontrollably leading to the overproduction of a single type of weak antibody. This causes various complications and weakens the immune system. Plasma cells in these conditions also have connections to related proteins like beta-2 microglobulin which serve as a marker to monitor disease progression. Understanding plasma cells and their roles can help in developing therapeutic approaches for these conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Plasma Cell
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Reproductive sciences (Thousand Oaks, Calif.) 21:63-71 PubMed23653390

2013

Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel M Kraus,Liping Feng,R Phillips Heine,Haywood L Brown,Kathleen M Caron,Amy P Murtha,Chad A Grotegut
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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