Reactivity 정보
특성 및 보관 정보
제형
Purity
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein is involved in the regulation of immune responses acting as an inhibitory receptor that impacts the signaling associated with phagocytic activity. It forms part of the cell signaling complex with SHP-1 and SHP-2 two phosphatases that modulate immune cell activation through dephosphorylation of specific sites. SWC8's function in signaling ensures proper modulation of immune responses balancing activation and inhibition to prevent excessive inflammation.
Pathways
Porcine SWC8 participates in immune response and signal transduction pathways. It is closely related to proteins involved in the SIRP (Signal Regulatory Protein) family pathway. This pathway includes interactions with other SIRP family proteins such as SIRPβ and CD47 which are critical for cell-cell communication and immune regulation. These interactions influence cell survival proliferation and migration playing an important role in maintaining immune homeostasis.
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Recent publications for all applications. Explore the 전체 목록 and refine your search
Journal of leukocyte biology 77:923-33 PubMed15767291
2005
Applications
Unspecified application
Species
Unspecified reactive species
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