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AB196275

Anti-PRELID1 antibody

5

(1 리뷰)

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(2 제품이 사용된 논문 )

Rabbit Polyclonal PRELID1 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PRELID1 aa 50 to C-terminus.

대체 명칭 보기

PRELI, CGI-106, SBBI12, PRELID1, 25 kDa protein of relevant evolutionary and lymphoid interest, Px19-like protein

1 이미지
Western blot - Anti-PRELID1 antibody (AB196275)
  • WB

Supplier Data

Western blot - Anti-PRELID1 antibody (AB196275)

All lanes:

Western blot - Anti-PRELID1 antibody (ab196275) at 1/500 dilution

All lanes:

K562 cell lysate

Predicted band size: 25 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human PRELID1 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9Y255

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보완 제품

Primary Antibodies

AB137616

Anti-AGK antibody

Immunocytochemistry/ Immunofluorescence - Anti-AGK antibody (AB137616)

  • 0
  • 0
Primary Antibodies

AB270268

Anti-Ornithine Decarboxylase/ODC antibody [ODC1/2878R]

Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ornithine Decarboxylase/ODC antibody [ODC1/2878R] (AB270268)

  • 5
  • 5
Primary Antibodies

AB109323

Anti-TRAP1 antibody [EPR5381]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP1 antibody [EPR5381] (AB109323)

  • 0
  • 0
Primary Antibodies

AB140595

Anti-TIA1 antibody [EPR9304]

KO Validated|RabMAb|Recombinant|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-TIA1 antibody [EPR9304] (AB140595)

  • 2
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Preservative: 0.02% Sodium azide Constituents: 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

PRELID1 also known as SLMO2 is a mitochondrial phospholipid transfer protein. This protein has a molecular mass of approximately 22 kDa and is expressed in various tissues with notable presence in the liver heart and skeletal muscle. Mechanically PRELID1 transfers phosphatidic acid from the outer to the inner mitochondrial membrane a process fundamental for maintaining mitochondrial lipid homeostasis.
Biological function summary

PRELID1 operates as part of a larger multi-protein complex within the mitochondria. It associates with other proteins like TRIT1 which together play a role in lipid metabolism and regulation. PRELID1's actions impact the synthesis of cardiolipin a critical lipid for mitochondrial inner membrane structure and function. By participating in these processes PRELID1 ensures proper mitochondrial activity and energy production.

Pathways

The activity of PRELID1 intersects with key pathways involved in lipid metabolism and mitochondrial function. Notably it plays a role in the CL (cardiolipin) remodeling pathway. Furthermore PRELID1 interacts with proteins such as TAMM41 a phosphatidic acid transfer protein which facilitates cardiolipin biosynthesis. These pathways are essential for the maintenance of mitochondrial membrane potential and cellular energy output.

Abnormalities in PRELID1 function connect to mitochondrial-related diseases including Barth syndrome and certain metabolic disorders. Research indicates its malfunction could link to altered cardiolipin synthesis affecting energy metabolism. Proteins involved in these conditions such as tafazzin play a role in cardiolipin remodeling highlighting the importance of PRELID1's function in maintaining healthy mitochondrial dynamics.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1 : PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.
See full target information PRELID1
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of molecular and cellular cardiology 167:1-14 PubMed35304170

2022

EFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia.

Applications

Unspecified application

Species

Unspecified reactive species

David R Eberhardt,Sandra H Lee,Xue Yin,Anthony M Balynas,Emma C Rekate,Jackie N Kraiss,Marisa J Lang,Maureen A Walsh,Molly E Streiff,Andrea C Corbin,Ying Li,Katsuhiko Funai,Frank B Sachse,Dipayan Chaudhuri

Translational oncology 11:786-793 PubMed29702465

2018

GALNT14 Involves the Regulation of Multidrug Resistance in Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jinshuai Shan,Yang Liu,Yukun Wang,Yimiao Li,Xiaochun Yu,Chen Wu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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