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AB316828

Anti-Protein Z antibody [EPR25824-8] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal Protein Z antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

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Vitamin K-dependent protein Z, PROZ

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Sandwich ELISA - Anti-Protein Z antibody [EPR25824-8] - BSA and Azide free (Detector) (AB316828)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Protein Z antibody [EPR25824-8] - BSA and Azide free (Detector) (AB316828)

Sandwich ELISA of ab316826 with the capture antibody ab316827 dilution at 2 ug/mL and detector antibody ab316828 dilution at 0.5 ug/mL.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR25824-8

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB137989

Human Protein Z ELISA Kit

ELISA - Human Protein Z ELISA Kit (AB137989)

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Primary Antibodies

AB316825

Anti-NFAT4/NF-ATc3 antibody [EPR25800-1] - BSA and Azide free (Detector)

Recombinant|RabMAb|KO Validated

Sandwich ELISA - Anti-NFAT4/NF-ATc3 antibody [EPR25800-1] - BSA and Azide free (Detector) (AB316825)

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  • 0
Primary Antibodies

AB316998

Anti-beta 2 Defensin/BD-2 antibody [EPR26637-70] - BSA and Azide free (Detector)

Recombinant|RabMAb

Sandwich ELISA - Anti-beta 2 Defensin/BD-2 antibody [EPR26637-70] - BSA and Azide free (Detector) (AB316998)

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  • 0
Primary Antibodies

AB316787

Anti-RUNX3 antibody [EPR24390-50] - BSA and Azide free (Detector)

Recombinant|RabMAb

Sandwich ELISA - Anti-RUNX3 antibody [EPR24390-50] - BSA and Azide free (Detector) (AB316787)

  • 0
  • 0
Primary Antibodies

AB316834

Anti-AMPK alpha 1 antibody [EPR26792-34] - BSA and Azide free (Detector)

Recombinant|RabMAb|KO Validated

Sandwich ELISA - Anti-AMPK alpha 1 antibody [EPR26792-34] - BSA and Azide free (Detector) (AB316834)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab316828 is a BSA and Azide free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human Protein Z. The recommended pair for sandwich ELISA is:

Capture: ab316827, Human Protein Z Capture Antibody (unconjugated)

Detector: ab316828, Human Protein Z Detector Antibody (unconjugated)

The reference range value is 31.25-2000 pg/mL.

The recommended antibody orientation is based on internal optimization for ELISA based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 - 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Protein Z also known as PZ is a vitamin K-dependent plasma protein with a molecular mass of approximately 62 kDa. It is primarily expressed in the liver and circulates in the blood. This protein plays a mechanical role in the coagulation system by interacting with the protein Z-dependent protease inhibitor which downregulates blood coagulation contributing to hemostasis. Protein Z is different from other coagulation proteins due to its lack of enzymatic activity but impacts the regulation of thrombin formation.
Biological function summary

Protein Z serves as a significant factor in the coagulation cascade being a part of the protein C pathway complex. Although it lacks enzymatic action Protein Z interacts with other proteins such as Factor Xa and Protein Z-dependent protease inhibitor to exert its effects. Its involvement helps modulate clot formation and stabilize the coagulation process impacting blood flow regulation.

Pathways

Protein Z is intricately linked to the coagulation and thrombosis pathways. It associates with proteins including Factor Xa and Protein C. Protein Z assists in regulating thrombin generation by inhibiting excess coagulation maintaining a balance within the hemostatic system. This interaction ensures the rapid and effective stopping of blood flow when required while preventing unwarranted thrombosis a critical aspect of circulatory system maintenance.

Protein Z levels link to thrombosis and hemorrhagic disorders. Abnormalities in Protein Z levels have connections with deep vein thrombosis due to its role in regulating coagulation balance. The protein Z-dependent protease inhibitor's association highlights its significance in clot formation and thrombosis prevention. Additionally deficiencies in Protein Z have connections with bleeding disorders emphasizing the protein's role in maintaining a balanced coagulation process essential for preventing excessive bleeding or clotting.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
See full target information PROZ
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Product promise

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