AB185236

Anti-PRSS8 antibody [EPR15327]

RabMAb
Recombinant
각 태그의 뜻

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(4 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal PRSS8 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 4 publications.

대체 명칭 보기

Prostasin, Channel-activating protease 1, Serine protease 8, CAP1, PRSS8

2 이미지

Supplier Data

Immunoprecipitation - Anti-PRSS8 antibody [EPR15327] (AB185236)

Western blot analysis of immunoprecipitation pellet from MCF7 cell lysate, immunoprecipitated using ab185235 at 1/50 dilution (lane 1) or PBS control (lane 2).
Secondary : Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution.

All lanes:

Immunoprecipitation - Anti-PRSS8 antibody [EPR15327] (ab185236)

Predicted band size: 36 kDa

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Supplier Data

Western blot - Anti-PRSS8 antibody [EPR15327] (AB185236)

All lanes:

Western blot - Anti-PRSS8 antibody [EPR15327] (ab185236) at 1/10000 dilution

Lane 1:

LnCAP cell lysate at 20 µg

Lane 2:

MCF7 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 36 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR15327

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IP

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/40 - 1/60", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).

See full target information Prostasin

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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular sciences 26: PubMed40003897

2025

Mint3 as a Molecular Target Activated in the Early Stage of Hepatocarcinogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Masaki Nishitani,Hikari Okada,Kouki Nio,Tomoyuki Hayashi,Takeshi Terashima,Noriho Iida,Tetsuro Shimakami,Hajime Takatori,Masao Honda,Shuichi Kaneko,Takeharu Sakamoto,Taro Yamashita

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2305907 PubMed38126621

2023

NNMT/1-MNA Promote Cell-Cycle Progression of Breast Cancer by Targeting UBC12/Cullin-1-Mediated Degradation of P27 Proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Yilei Ma,Xucheng Huang,Yanzhong Wang,Yinjiao Lei,Jinwei Yu,Shaobo Yu,Yuzhen Gao,Jun Yang,Feng Zhao,Haitao Yu,Jin Zeng,Yadong Chu,Min Yang,Guoli Li,Xinyou Xie,Jun Zhang

Journal of oncology 2022:8002318 PubMed35571488

2022

Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Zhu,Chao Jiang,Hongxia Hui,Yuan Sun,Mingyue Tao,Yangqing Liu,Xiaoping Qian

Bioengineered 12:9390-9400 PubMed34823420

2021

Knocking down Sterol regulatory element binding protein 2 (SREBF2) inhibits the Serine Protease 8 (PRSS8) /sodium channel epithelial 1alpha subunit (SCNN1A) axis to reduce the cell proliferation, migration and epithelial-mesenchymal transformation of ovarian cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Chunyan Cai,Yumei Zhang,Xing Peng

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PRSS8 antibody [EPR15327]

Immunoprecipitation - Anti-PRSS8 antibody [EPR15327] (AB185236)

Western blot - Anti-PRSS8 antibody [EPR15327] (AB185236)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (4)

Product promise