AB211292

Anti-PRX-1 antibody

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(19 제품이 사용된 논문 )

Rabbit Polyclonal PRX-1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 19 publications. Immunogen corresponding to Synthetic Peptide within Human PRRX1.

대체 명칭 보기

PMX1, PRRX1, Paired mesoderm homeobox protein 1, Homeobox protein PHOX1, Paired-related homeobox protein 1, PRX-1

2 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling PRX-1 with ab211292 at 10μg/ml.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling PRX-1 with ab211292 at 10μg/ml.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human PRRX1. The exact immunogen used to generate this antibody is proprietary information.

P54821

Specificity

At least two isoforms of PRX-1 are known to exist; ab211292 will detect both isoforms.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Orchestrates the functional drift of fibroblasts into myofibroblastic phenotype via TGF-beta signaling by remodeling a super-enhancer landscape. Through this function, plays an essential role in wound healing process (PubMed : 35589735). Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (By similarity). May play a role in homeostasis and regeneration of bone, white adipose tissue and derm (By similarity).. Isoform 1. Transcriptional activator, when transfected in fibroblastic or myoblastic cell lines. This activity may be masked by the C-terminal OAR domain.. Isoform 2. Transcriptional repressor, when transfected in fibroblastic or myoblastic cell lines.

See full target information PRRX1

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제품이 사용된 논문 (19)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Scientific reports 15:35547 PubMed41073566

2025

Total flavonoids of rhizoma drynariae improved the osteogenic and pro-angiogenic capacities of BMSCs to accelerate long bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Hengjun Huang,Silu Li,Huang Zhan,Fenfang Gong,Jian Liu,Zhenya Liu,Hui Li,Chengyu Yang

Protein & cell 16:667-684 PubMed40119681

2025

Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.

Applications

Unspecified application

Species

Unspecified reactive species

Min Wang,Zan He,Anqi Wang,Shuhui Sun,Jiaming Li,Feifei Liu,Chunde Li,Chengxian Yang,Jinghui Lei,Yan Yu,Shuai Ma,Si Wang,Weiqi Zhang,Zhengrong Yu,Guang-Hui Liu,Jing Qu

Bioactive materials 48:242-256 PubMed40046012

2025

An axolotl limb regeneration-inspired strategy to enhance alveolar bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Rongpu Liu,Guifang Wang,Li Ma,Guangzheng Yang,Sihan Lin,Ningjia Sun,Jiajia Wang,Huijing Ma,Xinquan Jiang,Wenjie Zhang

Journal of orthopaedic translation 48:11-24 PubMed39170748

2024

Hyperbaric oxygen promotes bone regeneration by activating the mechanosensitive Piezo1 pathway in osteogenic progenitors.

Applications

Unspecified application

Species

Unspecified reactive species

Hang Zhou,Hongzhi Liu,Minmin Lin,Hantang Wang,Jingjing Zhou,Ming Li,Xue Yang,Guibing Fu,Chao Liu

Biomedicines 12: PubMed38927412

2024

M2 Macrophages Guide Periosteal Stromal Cell Recruitment and Initiate Bone Injury Regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Dazhuang Lu,Yingfei Zhang,Shimin Liang,Yang Li,Jia Qing,Lanxin Gu,Xiuyun Xu,Zeying Wang,Xin Gao,Hao Liu,Xiao Zhang,Yongsheng Zhou,Ping Zhang

Frontiers in oncology 14:1383096 PubMed38846981

2024

Exploiting tertiary lymphoid structures gene signature to evaluate tumor microenvironment infiltration and immunotherapy response in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zhu Xu,Qin Wang,Yiyao Zhang,Xiaolan Li,Mei Wang,Yuhong Zhang,Yaxin Pei,Kezhen Li,Man Yang,Liping Luo,Chuan Wu,Weidong Wang

Journal of gastrointestinal oncology 13:2989-3008 PubMed36636075

2023

PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6.

Applications

Unspecified application

Species

Unspecified reactive species

Longzhu Zhong,Wanlin Tan,Qianqiong Yang,Zhaowei Zou,Rui Zhou,Yongsheng Huang,Zhenghua Qiu,Kehong Zheng,Zonghai Huang

Stem cell reports 17:2318-2333 PubMed36150383

2022

Single-cell spatiotemporal analysis reveals cell fates and functions of transplanted mesenchymal stromal cells during bone repair.

Applications

Unspecified application

Species

Unspecified reactive species

Chengyu Yang,Zeshun Li,Yang Liu,Runpeng Hou,Minmin Lin,Linhao Fu,Decheng Wu,Quanying Liu,Kai Li,Chao Liu

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36:e22530 PubMed36063128

2022

Controlled mechanical loading improves bone regeneration by regulating type H vessels in a S1Pr1-dependent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Chengyu Yang,Yang Liu,Ziyan Wang,Minmin Lin,Chao Liu

Frontiers in oncology 12:858694 PubMed35530319

2022

RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness Regulating p53.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangli Liu,Ziyi Wang,Qiwei Yang,Xiaohai Hu,Qiang Fu,Xinyu Zhang,Wenya Li

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PRX-1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRX-1 antibody (AB211292)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (19)

Product promise