AB2930

Anti-PSD93 antibody

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(7 제품이 사용된 논문 )

Rabbit Polyclonal PSD93 antibody. Suitable for IHC-Fr, WB, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus.

대체 명칭 보기

Dlgh2, Dlg2, Disks large homolog 2, Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Chapsyn-110

2 이미지

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF image of ab2930 stained PC12 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab2930, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

IHC-Fr

Supplier Data

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

Immunolocalization of PSD-93 in rat cerebellum using ab2930.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IHC-Fr, ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q63622

Specificity

Detects Post Synaptic Density 93 (PSD 93) from rat tissues. This antibody does not detect other synapse-associated protein family members.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCFr-species-checked": "testedAndGuaranteed", "IHCFr-species-dilution-info": "5 µg/mL", "IHCFr-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

Preservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

See full target information Dlg2

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제품이 사용된 논문 (7)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cells 12: PubMed36980245

2023

JNK Activation Correlates with Cognitive Impairment and Alteration of the Post-Synaptic Element in the 5xFAD AD Mouse Model.

Applications

Unspecified application

Species

Unspecified reactive species

Erica Cecilia Priori,Clara Alice Musi,Arianna Giani,Luca Colnaghi,Ivana Milic,Andrew Devitt,Tiziana Borsello,Mariaelena Repici

BMC biology 19:256 PubMed34911542

2021

JNK signaling provides a novel therapeutic target for Rett syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Clara Alice Musi,Anna Maria Castaldo,Anna Elisa Valsecchi,Sara Cimini,Noemi Morello,Riccardo Pizzo,Alessandra Renieri,Ilaria Meloni,Maurizio Bonati,Maurizio Giustetto,Tiziana Borsello

Cancer biology & therapy 20:897-911 PubMed30862230

2019

MicroRNA-23a depletion promotes apoptosis of ovarian cancer stem cell and inhibits cell migration by targeting DLG2.

Applications

Unspecified application

Species

Unspecified reactive species

Ru-Jin Zhuang,Xiao-Xu Bai,Wei Liu

Journal of Alzheimer's disease : JAD 63:1141-1159 PubMed29710724

2018

Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.

Applications

Unspecified application

Species

Unspecified reactive species

Yacoubou Abdoul Razak Mahaman,Fang Huang,Mengjuan Wu,Yuman Wang,Zhen Wei,Jian Bao,Maibouge Tanko Mahamane Salissou,Dan Ke,Qun Wang,Rong Liu,Jian-Zhi Wang,Bin Zhang,Dan Chen,Xiaochuan Wang

Cell death & disease 4:e673 PubMed23764854

2013

Glycation exacerbates the neuronal toxicity of β-amyloid.

Applications

Unspecified application

Species

Mouse

X-H Li,L-L Du,X-S Cheng,X Jiang,Y Zhang,B-L Lv,R Liu,J-Z Wang,X-W Zhou

The Journal of neuroscience : the official journal of the Society for Neuroscience 31:6800-8 PubMed21543610

2011

PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.

Applications

ICC/IF

Species

Rat

Qian Sun,Gina G Turrigiano

Journal of Cancer 1:14-22 PubMed20842219

2010

Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26.

Applications

Species

Human

Ziad J Sahab,Michael D Hall,Lihua Zhang,Amrita K Cheema,Stephen W Byers

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PSD93 antibody

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (7)

Product promise