AB172628

Anti-PSD95 (phospho T19) antibody [EPR2619(2)]

Name: Anti-PSD95 (phospho T19) antibody [EPR2619(2)]
Brand: Abcam Limited
SKU: AB172628
Rating: 5 (1 reviews)

20ul selling size
RabMAb
Recombinant
각 태그의 뜻

(1 리뷰)

(5 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal PSD95 phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

1 이미지

Supplier Data

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)

All lanes:

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628) at 1/1000 dilution

Lane 1:

Fetal brain lysate, untreated at 10 µg

Lane 2:

Fetal brain lysate, treated with Lambda Phosphatase at 10 µg

Predicted band size: 80 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR2619(2)

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (PubMed : 26334723).

See full target information DLG4 pT19

대체 명칭 보기

PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90

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제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록and refine your search

Brain research bulletin 165:272-280 PubMed33075417

2020

Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hasan Alhaddad,Fawaz Alasmari,Balsam Alhamadani,Woonyen Wong,Richard L Bell,Youssef Sari

Frontiers in cellular neuroscience 13:447 PubMed31749684

2019

Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Mice Contributes to Synaptic and Social Deficiency.

Applications

Unspecified application

Species

Unspecified reactive species

Mengmeng Wang,Xinyan Liu,Yilin Hou,Haifeng Zhang,Junjun Kang,Fei Wang,Youyi Zhao,Jing Chen,Xufeng Liu,Yazhou Wang,Shengxi Wu

The EMBO journal 37:122-138 PubMed29118000

2017

Ca/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down.

Applications

Unspecified application

Species

Unspecified reactive species

Dhrubajyoti Chowdhury,Matthew Turner,Tommaso Patriarchi,Anne C Hergarden,David Anderson,Yonghong Zhang,Junqing Sun,Chao-Yin Chen,James B Ames,Johannes W Hell

Frontiers in molecular neuroscience 10:295 PubMed28979184

2017

SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.

Applications

Unspecified application

Species

Unspecified reactive species

Dae Hwan Kim,Minkyung Kang,Chong-Hyun Kim,Yun Hyun Huh,In Ha Cho,Hyun-Hee Ryu,Kyung Hwun Chung,Chul-Seung Park,Sangmyung Rhee,Yong-Seok Lee,Woo Keun Song

Bipolar disorders 18:473-480 PubMed27687706

2016

Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Eléonore Beurel,Steven F Grieco,Celeste Amadei,Kimberlee Downey,Richard S Jope

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PSD95 (phospho T19) antibody [EPR2619(2)]

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (5)

Product promise