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AB244289

Anti-RAP1/TERF2IP antibody

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(1 출판물)

Rabbit Polyclonal RAP1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TERF2IP aa 250 to C-terminus.

대체 명칭 보기

DRIP5, RAP1, PP8000, TERF2IP, Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric protein 1, Dopamine receptor-interacting protein 5, Repressor/activator protein 1 homolog, RAP1 homolog, hRap1

4 이미지
Immunocytochemistry/ Immunofluorescence - Anti-RAP1/TERF2IP antibody (AB244289)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-RAP1/TERF2IP antibody (AB244289)

PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for RAP1/TERF2IP (green) using ab244289 at 4 μg/ml in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1/TERF2IP antibody (AB244289)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1/TERF2IP antibody (AB244289)

Paraffin-embedded human lymph node tissue stained for RAP1/TERF2IP using ab244289 at 1/50 dilution in immunohistochemical analysis.

Western blot - Anti-RAP1/TERF2IP antibody (AB244289)
  • WB

Unknown

Western blot - Anti-RAP1/TERF2IP antibody (AB244289)

All lanes:

Western blot - Anti-RAP1/TERF2IP antibody (ab244289) at 0.4 µg/mL

All lanes:

SCLC-21H cell lysate

Predicted band size: 44 kDa

false

Western blot - Anti-RAP1/TERF2IP antibody (AB244289)
  • WB

Unknown

Western blot - Anti-RAP1/TERF2IP antibody (AB244289)

All lanes:

Western blot - Anti-RAP1/TERF2IP antibody (ab244289) at 0.4 µg/mL

Lane 1:

Vector only transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

Lane 2:

RAP1 over-expression HEK-293T cell lysate

Predicted band size: 44 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF, WB

applications

Immunogen

Recombinant Fragment Protein within Human TERF2IP aa 250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9NYB0

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대체품

Primary Antibodies

AB14404

Anti-RAP1/TERF2IP antibody [4c8/1]

Flow Cytometry - Anti-RAP1/TERF2IP antibody [4c8/1] (AB14404)

  • 5
  • 4
Primary Antibodies

AB113480

Anti-RAP1/RABGEF1 antibody

Western blot - Anti-RAP1/RABGEF1 antibody (AB113480)

  • 0
  • 0
Primary Antibodies

AB175329

Anti-RAP1A antibody [1D2-1C64]

Immunocytochemistry/ Immunofluorescence - Anti-RAP1A antibody [1D2-1C64] (AB175329)

  • 0
  • 0

보완 제품

Primary Antibodies

AB175329

Anti-RAP1A antibody [1D2-1C64]

Immunocytochemistry/ Immunofluorescence - Anti-RAP1A antibody [1D2-1C64] (AB175329)

  • 0
  • 0
Primary Antibodies

AB113480

Anti-RAP1/RABGEF1 antibody

Western blot - Anti-RAP1/RABGEF1 antibody (AB113480)

  • 0
  • 0
Primary Antibodies

AB10579

Anti-TRF2 + TRF1 antibody [TRF-78]

Immunocytochemistry/ Immunofluorescence - Anti-TRF2 + TRF1 antibody [TRF-78] (AB10579)

  • 5
  • 10
Primary Antibodies

AB108997

Anti-TRF2 antibody [EPR3517(2)]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-TRF2 antibody [EPR3517(2)] (AB108997)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cynomolgus monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Does not bind DNA directly : recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres, also acts as a transcription regulator : recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes.
See full target information TERF2IP
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Bioscience reports 41: PubMed34505628

2021

Identification of CCT3 as a prognostic factor and correlates with cell survival and invasion of head and neck squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wang,Peicheng Liu,Ziwei Zhang,Jiulong Wang,Zhigang Cheng,Chengchao Fan
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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