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- Flow Cyt
Supplier Data
Flow Cytometry - redFluor™ 710 Anti-CD11c antibody [3.9] (AB241936)
Flow cytometric analysis of human peripheral blood lymphocytes stained for CD11c with 5 μl (1.0 μg) ab241936 (solid line) or 1.0 μg redFluor™ 710 Mouse IgG1 isotype control (dashed line).
관련 conjugated 항체와 다양한 조성의 항체 (2)
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785 APC/Cy7®
APC/Cy7® Anti-CD11c antibody [3.9]
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450 violetFluor™ 450
violetFluor™ 450 Anti-CD11c antibody [3.9]
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Purification 테크닉
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보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD11c functions as an integrin alpha X subunit forming a heterodimer with the beta 2 subunit known as ITGB2. This complex is important for cell adhesion and migration processes. It mediates the binding of leukocytes to endothelial cells facilitating their migration from the bloodstream to sites of inflammation or infection. CD11c's presence on immune cells makes it essential for presenting antigens and initiating immune responses therefore having critical implications for immunity.
Pathways
CD11c plays a significant role in the immune system particularly in the leukocyte adhesion and migration pathways. It partners with proteins like ITGB2 to mediate these functions. The signaling pathways involving CD11c and related molecules regulate leukocyte trafficking and activation ensuring proper localization and function at sites of damage or infection. These pathways are essential for maintaining immune homeostasis and prompt responses to pathogens.
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