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AB237689

Anti-REEP4 antibody

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Rabbit Polyclonal REEP4 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human REEP4 aa 50 to C-terminus.

대체 명칭 보기

C8orf20, PP432, REEP4, Receptor expression-enhancing protein 4

4 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)

Paraffin-embedded human testis tissue stained for REEP4 using ab237689 at 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-REEP4 antibody (AB237689)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-REEP4 antibody (AB237689)

HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for REEP4 (Green) using ab237689 at 1/100 dilution in ICC/IF, followed by an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)

Paraffin-embedded human adrenal gland tissue stained for REEP4 using ab237689 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-REEP4 antibody (AB237689)

Paraffin-embedded human small intestine tissue stained for REEP4 using ab237689 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF, WB

applications

Immunogen

Recombinant Fragment Protein within Human REEP4 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9H6H4

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보완 제품

Primary Antibodies

AB96359

Anti-Glycogenin 2 antibody

Western blot - Anti-Glycogenin 2 antibody (AB96359)

  • 0
  • 0
Primary Antibodies

AB121718

Anti-MSL1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-MSL1 antibody (AB121718)

  • 5
  • 1
Primary Antibodies

AB254937

Anti-FAM5C antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM5C antibody (AB254937)

  • 0
  • 0
Primary Antibodies

AB251967

Anti-PADI1 / PAD1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PADI1 / PAD1 antibody (AB251967)

  • 0
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity greater than 95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

REEP4 also known as Receptor Expression Enhancing Protein 4 is a protein that assists in shaping the endoplasmic reticulum. It has a molecular mass of approximately 27 kDa. REEP4 is predominantly expressed in various tissues with notable expression in the brain and testes. Through its role REEP4 helps maintain the architecture of organelles essential for proper cellular function.
Biological function summary

In shaping the endoplasmic reticulum REEP4 interacts with other proteins significantly impacting the division and separation of the organelle during cell division. This protein is part of a complex that facilitates the proper distribution of the endoplasmic reticulum in dividing cells. Through these interactions REEP4 ensures that cells maintain proper functionality and organelle distribution which are important in various cellular processes.

Pathways

The endoplasmic reticulum shaping involving REEP4 affects the spindle assembly checkpoint and mitotic division. This involves pathways like those related to cell cycle regulation. REEP4 shares functional connections with proteins such as DPYSL2 and CLIMP-63. These interactions play an essential role in maintaining cellular architecture during mitosis ensuring proper cell division and distribution of cellular contents.

Misregulation of REEP4 can have effects on cell division and may be linked to disorders such as cancer and neurodegenerative diseases. Variations in REEP4 function or expression could influence these conditions due to its role in the structural integrity of the endoplasmic reticulum. Additionally dysfunction in REEP4 can relate to proteins like tau in the context of neurodegenerative diseases suggesting a possible pathophysiological connection through endoplasmic reticulum stress or imbalance during cell cycle processes.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
See full target information REEP4
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancer medicine 12:4968-4980 PubMed36056909

2022

Risk stratification and prognosis prediction based on inflammation-related gene signature in lung squamous carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Wenyu Zhai,Si Chen,Fangfang Duan,Junye Wang,Zerui Zhao,Yaobin Lin,Bingyu Rao,Yizhi Wang,Lie Zheng,Hao Long
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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