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AB197361

Anti-RELM beta antibody

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Rabbit Polyclonal RELM beta antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RETNLB.

대체 명칭 보기

CCRG, FIZZ2, HXCP2, RETNL2, UNQ408/PRO770, RETNLB, Resistin-like beta, Colon and small intestine-specific cysteine-rich protein, Colon carcinoma-related gene protein, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, RELMbeta

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (AB197361)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (AB197361)

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling RELM beta with ab197361 at 1/40 dilution

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (AB197361)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (AB197361)

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling RELM beta with ab197361 at 1/40 dilution.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human RETNLB. The exact immunogen used to generate this antibody is proprietary information.

Q9BQ08

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대체품

Primary Antibodies

AB11429

Anti-RELM beta antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RELM beta antibody (AB11429)

  • 0
  • 0

보완 제품

Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

  • 0
  • 0
Primary Antibodies

AB199428

Anti-GATA3 antibody [EPR16651] - ChIP Grade

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Western blot - Anti-GATA3 antibody [EPR16651] - ChIP Grade (AB199428)

  • 5
  • 14
Primary Antibodies

AB313900

Alexa Fluor® 488 Anti-CD11c antibody [KB90]

Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-CD11c antibody [KB90] (AB313900)

  • 0
  • 0
Proteins & Peptides

AB269151

Recombinant Human RELM beta protein

SDS-PAGE - Recombinant Human RELM beta protein (AB269151)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/40 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

RELM beta also known as Resistin-Like Molecule Beta or FIZZ2 is a cysteine-rich secreted protein with an approximate mass of 19 kDa. This protein expresses mainly in tissues like the colon small intestine and adipose tissue. It belongs to the resistin-like molecule (RELM) family which is known for its similarities in amino acid sequence and structural features. RELM beta usually gets secreted by epithelial cells particularly in the intestinal region which suggests its active involvement in the gut environment.
Biological function summary

The RELM beta protein modulates immune responses and interacts with elements of the metabolic processes. It plays a role in bridging innate and adaptive immunity affecting inflammatory cascades through its cytokine-like activities. Although it is not part of a large complex RELM beta influences receptor signaling pathways and can affect macrophages and other immune cells. Its activity on energy homeostasis and glucose metabolism indicates key interactions in metabolic pathways influencing overall cellular functions.

Pathways

RELM beta prominently interacts with pathways involved in inflammation and metabolism. It participates in the NF-kB signaling pathway which is a central mediator in inflammation and immune responses. Also it connects to the adipokine signaling pathway where it works alongside other resistin family proteins. Through these pathways RELM beta coordinates with proteins like TNF-alpha and IL-6 in modulating inflammation and energy balance.

RELM beta relates to conditions such as inflammatory bowel disease (IBD) and type 2 diabetes. Its increased expression associates with elevated inflammatory states found in IBD and insights suggest a role in disease progression through interactions with proteins like IL-1β. In type 2 diabetes the regulation of glucose homeostasis implicates RELM beta as a participant in metabolic dysregulation. Changes in RELM beta expression can influence risk factors potentially in conjunction with other mediators like insulin.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Probable hormone.
See full target information RETNLB
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Genes & diseases 9:705-716 PubMed35782979

2020

Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development.

Applications

Unspecified application

Species

Unspecified reactive species

Shanshan Wang,Qian Hao,Jiajia Li,Yajie Chen,Hua Lu,Xiaohua Wu,Xiang Zhou
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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