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AB106360

Anti-RGPD5 antibody

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Rabbit Polyclonal RGPD5 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human RGPD5.

대체 명칭 보기

RANBP2L1, RGP5, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, RGPD5, RANBP2-like and GRIP domain-containing protein 5/6, Ran-binding protein 2-like 1/2, Sperm membrane protein BS-63, RanBP2-like 1/2, RanBP2L1, RanBP2L2

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RGPD5 antibody (AB106360)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RGPD5 antibody (AB106360)

ab106360 at 10 μg/ml staining RGPD5 in Human testis tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Immunocytochemistry/ Immunofluorescence - Anti-RGPD5 antibody (AB106360)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-RGPD5 antibody (AB106360)

Immunofluorescence of RGPD5 in Human testis tissue with ab106360 at 20 ug/mL.

Western blot - Anti-RGPD5 antibody (AB106360)
  • WB

Unknown

Western blot - Anti-RGPD5 antibody (AB106360)

All lanes:

Western blot - Anti-RGPD5 antibody (ab106360) at 1 µg/mL

All lanes:

Human thymus tissue lysate at 15 µg

Predicted band size: 199 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human RGPD5. The exact immunogen used to generate this antibody is proprietary information.

Q99666

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보완 제품

Primary Antibodies

AB126538

Anti-LOX 1 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOX 1 antibody (AB126538)

  • 0
  • 0
Primary Antibodies

AB31457

Anti-Neurofascin antibody

Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neurofascin antibody (AB31457)

  • 4
  • 4
Primary Antibodies

AB134128

Anti-Semaphorin 4D/CD100 antibody [EP3569]

KO Validated|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Semaphorin 4D/CD100 antibody [EP3569] (AB134128)

  • 0
  • 0
Primary Antibodies

AB53278

Anti-ALDH7A1 antibody [EP1935Y]

BOND RX™ Validated|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-ALDH7A1 antibody [EP1935Y] (AB53278)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "20 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
Affinity chromatography purified via peptide column
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
Up to 12 months
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

RGPD5 also known as RANBP2-like and GRIP domain-containing protein 5 plays a role in nucleocytoplasmic transport. The protein facilitates the movement of molecules between the nucleus and the cytoplasm which is important for many cellular processes. RGPD5 has a molecular mass of approximately 178 kDa. This protein is expressed in various tissues with significant expression noted in the testis brain and liver. Such expression patterns suggest its involvement in multiple biological functions within these tissues.
Biological function summary

RGPD5 contributes to cellular regulation and gene expression. The protein is part of the nuclear pore complex which is important for the transport of macromolecules across the nuclear envelope. This involvement indicates its key role in maintaining the communication between the nucleus and the cytoplasm. The role in the nuclear pore complex links RGPD5 to the cell cycle and RNA metabolism as these processes require controlled transport of specific factors across the nuclear envelope.

Pathways

RGPD5 integrates itself into pathways that govern cell cycle regulation and RNA processing. It associates with nuclear transport pathways that are essential for the proper localization of proteins and RNA which affects their function. RGPD5 connects with other nuclear transport proteins such as importins and exportins to support its role in nucleocytoplasmic exchange. The interplay with these proteins ensures correct cellular responses to environmental and developmental signals.

RGPD5 associates with conditions such as neurological disorders and infertility. Links to these diseases arise from its expression patterns and involvement in tissue-specific regulation. Alterations in RGPD5 function or expression may disrupt nuclear transport impacting neurons or reproductive cells severely. Connections with disorders involve proteins like RAN a transport GTPase which directly affects nuclear-cytoplasmic transport when RGPD5 activity is altered resulting in possible pathological states.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information RGPD5
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancers 13: PubMed33435319

2021

Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent and Copy Gain in Medullary Thyroid Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Aline Neves Araujo,Cléber Pinto Camacho,Thais Biude Mendes,Susan Chow Lindsey,Lais Moraes,Marta Miyazawa,Rosana Delcelo,Renata Pellegrino,Diego Robles Mazzotti,Rui Monteiro de Barros Maciel,Janete Maria Cerutti
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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