Anti-RPS15A antibody

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This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

RPS15A contributes significantly to the formation and function of ribosomes. It is part of the ribosomal protein complex that assembles with rRNA to create functional ribosomes which perform cellular protein synthesis. Ribosomal proteins including RPS15A ensure the correct assembly and stability of ribosomal subunits influencing the efficiency and fidelity of translation. The robustness of translational machinery relies on RPS15A and similar proteins to carry out high-fidelity protein synthesis which is important for cell growth and proliferation.

Pathways

RPS15A is an important player in the cellular process of translation. It is involved in the mTOR signaling pathway important for regulating cell growth and metabolism. The mTOR pathway responds to nutrients and growth signals by modifying the function of ribosome-related proteins including RPS15A. Another significant pathway is the p53 signaling pathway where RPS15A intersects through its role in maintaining protein synthesis even when stress responses are activated. Interactions with proteins such as ribosomal protein S6 and other ribosomal constituents highlight the importance of RPS15A in coordinating cellular metabolic activities.