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AB22055

Anti-SARS Envelope Protein antibody - Coronavirus

4

(2 리뷰들)

|

(1 출판물)

Rabbit Polyclonal VEMP antibody. Suitable for WB and reacts with SARS-CoV samples. Cited in 1 publication.
1 이미지
Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)
  • WB

Unknown

Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)

All lanes:

Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (ab22055) at 1 µg/mL

Observed band size: 16 kDa,32 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

SARS-CoV

Applications

WB

applications

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "SARS-CoV": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

제품 세부 정보

Applications overview

Tick: Tested and Guaranteed to work X: Will not work —: No data Reviews: Customers have been successful and shared their AbReview

<img src="https://www.abcam.com/ps/Products/22/ab22055/Images/ab22055-394526-applications-overview.jpg" height="125" width="675">

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
보관 버퍼
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.2% Gelatin
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The SARS Envelope Protein also known as E protein plays an essential role in the mechanical structure and function of the coronavirus. The protein has a mass of approximately 8.4 kDa and is expressed in the envelope of the virus. It functions as a viroporin creating ion channels that are important for the virus's lifecycle. These channels facilitate the transport of ions across the viral membrane contributing to the virus's assembly and budding processes.
Biological function summary

The SARS Envelope Protein exhibits significant functionality in viral pathogenesis and host interaction. It forms part of a larger protein complex in the viral envelope works alongside other structural proteins like the membrane (M) protein and nucleocapsid (N) protein. Through these actions the E protein influences coronavirus virulence assisting in virus-host interactions and the evasion of the host immune response.

Pathways

The SARS Envelope Protein actively participates in viral replication and assembly pathways. It interacts with host cell machinery to modulate viral and host processes important for replication. It also potentially influences the NF-kB signaling pathway which can affect host inflammation response. Related proteins include the spike (S) protein which helps the virus attach and enter host cells indicating a combined effort in infection spread.

The SARS Envelope Protein has a direct connection to illnesses such as COVID-19 and Severe Acute Respiratory Syndrome (SARS). The protein's role in viral assembly and immune evasion links it to the severity and transmission of these diseases. It is also connected to the IFN path where it can interfere with the host's interferon response a critical aspect of antiviral defense. These interactions make the SARS Envelope Protein a potential target for therapeutic interventions.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of immunology (Baltimore, Md. : 1950) 176:2346-56 PubMed16455992

2006

CCL5 modulates pneumococcal immunity and carriage.

Applications

Unspecified application

Species

Unspecified reactive species

Ravichandran Palaniappan,Shailesh Singh,Udai P Singh,Rajesh Singh,Edwin W Ades,David E Briles,Susan K Hollingshead,Walter Royal,Jacquelyn S Sampson,Jonathan K Stiles,Dennis D Taub,James W Lillard
제품이 사용된 논문 모두 보기

Product promise

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