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AB90238

Anti-SCGF antibody [MM0533-6D5]

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(2 제품이 사용된 논문 )

Mouse Monoclonal SCGF antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CLEC11A.
1 이미지
Western blot - Anti-SCGF antibody [MM0533-6D5] (AB90238)
  • WB

Supplier Data

Western blot - Anti-SCGF antibody [MM0533-6D5] (AB90238)

All lanes:

Western blot - Anti-SCGF antibody [MM0533-6D5] (ab90238) at 1/500 dilution

All lanes:

Human placenta tissue lysate

Predicted band size: 35 kDa

false

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MM0533-6D5

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CLEC11A.

Q9Y240

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대체품

Primary Antibodies

AB238830

Anti-SCGF antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCGF antibody (AB238830)

  • 0
  • 0

보완 제품

Assay Kits

AB314388

Human SCGF ELISA Kit

Sandwich ELISA - Human SCGF ELISA Kit (AB314388)

  • 0
  • 0
Primary Antibodies

AB203491

Anti-PDGFR alpha antibody [EPR22059-270]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDGFR alpha antibody [EPR22059-270] (AB203491)

  • 4
  • 7
Primary Antibodies

AB138492

Anti-Collagen I antibody [EPR7785]

20ul selling size|BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Frozen sections) - Anti-Collagen I antibody [EPR7785] (AB138492)

  • 4
  • 37
Primary Antibodies

AB192029

Anti-Ym-1 + Ym-2 antibody [EPR15263]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ym-1 + Ym-2 antibody [EPR15263] (AB192029)

  • 5
  • 2
Primary Antibodies

AB199056

Anti-Fibronectin antibody [EPR19241-46]

20ul selling size|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibronectin antibody [EPR19241-46] (AB199056)

  • 4
  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Stem Cell Growth Factor (SCGF) also known as C-type lectin domain family 11 member A (CLEC11A) is a glycoprotein with a mass around 38 kDa. It mechanically functions by promoting mitogenic and survival activities on hematopoietic progenitors which are essential for blood cell formation. SCGF is mainly expressed in the bone marrow as well as in several other tissues such as the pancreas and liver where it plays significant roles.
Biological function summary

SCGF plays a significant role in the development and regulation of the hematopoietic system. It supports the proliferation and differentiation of a variety of blood cell lineages. SCGF does not belong to a complex but interacts with other soluble factors like cytokines and growth factors to exert its functions. It enhances the actions of colony-stimulating factors emphasizing its role in hematopoiesis.

Pathways

SCGF is important in the regulation of the hematopoietic growth pathways. It is involved in the cytokine-cytokine receptor interaction pathway which assists in signaling and communication between cells. SCGF shows interactions with proteins like FLT3 which play a role in the development and survival of blood cell precursors. This intricate network bolsters the adaptive and innate immune systems by promoting the production and function of necessary blood cells.

Disruptions in SCGF activity can influence both hematological and autoimmune disorders. Alterations in SCGF expression have connections to leukemia where abnormal proliferation of blood cells occurs. Additionally its dysregulation may contribute to autoimmune diseases where the immune system mistakenly attacks the body. In these contexts SCGF relates with the cytokine IL-6 which is also involved in immune responses and inflammation further underlining SCGF's influence on disease mechanisms.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed : 27976999). Important for repair and maintenance of adult bone (By similarity).
See full target information CLEC11A

대체 명칭 보기

CLECSF3, LSLCL, SCGF, CLEC11A, C-type lectin domain family 11 member A, C-type lectin superfamily member 3, Lymphocyte secreted C-type lectin, Osteolectin, Stem cell growth factor, p47
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Genes 13: PubMed35456465

2022

Transcriptome Profile of Membrane and Extracellular Matrix Components in Ligament-Fibroblastic Progenitors and Cementoblasts Differentiated from Human Periodontal Ligament Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Seyoung Mun,Seong Min Kim,Min-Jeong Choi,Young-Joo Jang

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 75:298-308 PubMed27546031

2016

Genetic Analysis of Giant Cell Lesions of the Maxillofacial and Axial/Appendicular Skeletons.

Applications

Unspecified application

Species

Unspecified reactive species

Zachary S Peacock,Joseph H Schwab,William C Faquin,Francis J Hornicek,Yair Benita,David H Ebb,Leonard B Kaban
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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