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AB244770

Anti-Serum Amyloid P/SAP antibody [EPR21772-79] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal Serum Amyloid P/SAP antibody. Carrier free. Suitable for sELISA and reacts with Mouse samples.

대체 명칭 보기

Ptx2, Sap, Apcs, Serum amyloid P-component, SAP

1 이미지
Sandwich ELISA - Anti-Serum Amyloid P/SAP antibody [EPR21772-79] - BSA and Azide free (Capture) (AB244770)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Serum Amyloid P/SAP antibody [EPR21772-79] - BSA and Azide free (Capture) (AB244770)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab235639).

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR21772-79

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB235639

Mouse SAP ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse SAP ELISA Kit (AB235639)

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Primary Antibodies

AB242353

Anti-S100A8 antibody [EPR22333-115] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-S100A8 antibody [EPR22333-115] - BSA and Azide free (Detector) (AB242353)

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  • 0
Assay Kits

AB246537

Human SAP ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human SAP ELISA Kit (AB246537)

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  • 0
Proteins & Peptides

AB316604

Recombinant Mouse Calprotectin Protein Standard (His tag)

Sandwich ELISA - Recombinant Mouse Calprotectin Protein Standard (His tag) (AB316604)

  • 0
  • 0
Proteins & Peptides

AB283899

Recombinant Human Fas Ligand Protein

SDS-PAGE - Recombinant Human Fas Ligand Protein (AB283899)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab244770 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse SAP. The recommended pair for sandwich ELISA is:
Capture: ab244770, Mouse SAP Capture Antibody (unconjugated)
Detector: ab245042, Mouse SAP Detector Antibody (unconjugated)
The reference range value is 62.5 - 4000 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Serum Amyloid P component also known as SAP P-SAP or APCS protein is a pentraxin family member. It has a molecular mass of approximately 25 kDa. SAP expresses mainly in the liver and circulates in blood plasma. The protein consists of five identical subunits which form a homopentameric structure. This structure enables SAP to bind to amyloid fibrils a defining mechanical action of this protein.
Biological function summary

SAP plays a role in the immune system by recognizing damaged cells and pathogens. It acts as an opsonin marking these cellular targets for phagocytosis. As part of a complex SAP stabilizes extracellular matrix and amyloid deposits. It binds specifically to amyloid fibrils found in various tissues potentially facilitating their removal by immune cells. The protein's binding actions are important for its role in maintaining tissue and fluid homeostasis.

Pathways

SAP is actively involved in the innate immune response and amyloidogenic pathways. It interacts with the complement system to enhance the clearance of cell debris and amyloid fibrils. The complement system is an important component of innate immunity where SAP can engage with complement proteins like C1q. This interaction suggests that SAP plays roles in modulating both inflammation and tissue repair processes.

SAP has significant connections. SAP is related to systemic amyloidosis where it binds to amyloid deposits affecting multiple organs. Moreover SAP has been implicated in Alzheimer's disease due to its interaction with beta-amyloid protein plaques. In these disorders the involvement of SAP aids researchers in understanding the pathological mechanisms and could open avenues for targeted therapies aimed at modulating SAP functions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Apcs
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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