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AB235004

Anti-SLC22A23 antibody

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Rabbit Polyclonal SLC22A23 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SLC22A23 aa 1-250.

대체 명칭 보기

C6orf85, SLC22A23, Solute carrier family 22 member 23

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC22A23 antibody (AB235004)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC22A23 antibody (AB235004)

Paraffin-embedded human small intestine tissue stained for SLC22A23 using ab235004 at 1/200 dilution in immunohistochemical analysis.

After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. Staining was performed on a Leica BondTM system. The primary is detected by a biotinylated secondary antibody and visualized tissue using an HRP conjugated SP system.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human SLC22A23 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

A1A5C7

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보완 제품

Primary Antibodies

AB36893

Anti-CTRP5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CTRP5 antibody (AB36893)

  • 5
  • 3
Primary Antibodies

AB124826

Anti-SLC22A3/OCT3 antibody [EPR6630]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLC22A3/OCT3 antibody [EPR6630] (AB124826)

  • 0
  • 0
Primary Antibodies

AB200641

Anti-SLC22A4/ETT antibody

Western blot - Anti-SLC22A4/ETT antibody (AB200641)

  • 0
  • 0
Primary Antibodies

AB241544

Anti-SA1 antibody [SUSI63B]

Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SA1 antibody [SUSI63B] (AB241544)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

SLC22A23 also known as OCTN-R1 is a member of the solute carrier family 22. This protein weighs around 61 kDa and facilitates the transport of organic cations. It operates by transferring small molecules across cellular membranes. SLC22A23 shows expression in a variety of tissues including the liver kidneys and brain suggesting a wide functional role within the human body.
Biological function summary

SLC22A23 impacts cellular homeostasis and detoxification processes by managing the cellular intake and expulsion of endogenous and exogenous molecules. Currently there is limited evidence that it forms part of a larger protein complex; however its solute transport function highlights its role in maintaining cellular balance and protecting cells from harmful compounds. It supports essential biological processes by interfacing with other transport proteins within the cell.

Pathways

SLC22A23 participates in the organic cation transport pathway which is essential for xenobiotic metabolism. This pathway includes key interactions with other transporters such as SLC22A1 and SLC22A2 which similarly manage the movement of organic cations. Another pathway that involves SLC22A23 is related to drug metabolism wherein it assists in mediating the clearance of pharmaceutical compounds.

SLC22A23 has been connected to renal dysfunction and certain neurodegenerative diseases due to its pivotal role in solute transportation. Aberrations in its function can lead to improper detoxification contributing to renal impairment. Additionally the protein's expression in the brain suggests a possible link to neurodegenerative issues with interactions involving proteins like SLC22A4 which has implications for similar disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information SLC22A23
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Experimental dermatology 31:1253-1263 PubMed35514241

2022

Silencing of Rab23 by siRNA inhibits ultraviolet B-induced melanogenesis via downregulation of PKA/CREB/MITF.

Applications

Unspecified application

Species

Unspecified reactive species

Xuanjin Wei,Min Huang,Yi Yang,Yali Liu,Sumin Chi,Chengxin Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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