AB235166

Anti-Ferroportin antibody

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(7 제품이 사용된 논문 )

Rabbit Polyclonal SLC40A1 antibody. Suitable for WB and reacts with Human samples. Cited in 7 publications.

대체 명칭 보기

FPN, FPN1, IREG1, SLC11A3, MSTP079, SLC40A1, Ferroportin, Ferroportin-1, Iron-regulated transporter 1, Solute carrier family 40 member 1

1 이미지

Supplier Data

Western blot - Anti-Ferroportin antibody (AB235166)

All lanes:

Western blot - Anti-Ferroportin antibody (ab235166) at 5 µg/mL

Lane 1:

CACO2 (Human colorectal adenocarcinoma cell line) whole cell lysate at 35 µg

Lane 2:

K562 (Human chronic myelogenous leukemia cell line from bone marrow ) whole cell lysate at 35 µg

Lane 3:

HepG2 (Human liver hepatocellular carcinoma cell line) whole cell lysate at 35 µg

Lane 4:

MCF7 (Human breast adenocarcinoma cell line) whole cell lysate at 35 µg

Secondary

All lanes:

Goat anti-Rabbit IgG [H&L] HRP at 1/70000 dilution

Predicted band size: 63 kDa

false

Exposure time: 40s

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "5 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification

보관 버퍼

Preservative: 0.01% Sodium azide Constituents: PBS

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed : 15692071, PubMed : 22178646, PubMed : 22682227, PubMed : 24304836, PubMed : 29237594, PubMed : 29599243, PubMed : 30247984). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed : 22682227, PubMed : 29237594, PubMed : 32814342).

See full target information Ferroportin

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제품이 사용된 논문 (7)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Physiological reports 13:e70580 PubMed40999314

2025

High-intensity interval training attenuates cardiac injury by targeting ferroptosis and endoplasmic reticulum-stress in male rats with heart failure.

Applications

Unspecified application

Species

Unspecified reactive species

Aida Sabouri,Abbasali Gaeini,Soheila Adeli,Alireza Ghardashi Afousi

Oncology letters 28:298 PubMed38751752

2024

Mechanism of targeting the mTOR pathway to regulate ferroptosis in NSCLC with different EGFR mutations.

Applications

Unspecified application

Species

Unspecified reactive species

Chunjiao Wu,Rui Zhong,Tianxue Wei,Yulong Jin,Chunying He,Hui Li,Ying Cheng

Frontiers in cell and developmental biology 11:1272667 PubMed38033861

2023

Iron affects the sphere-forming ability of ovarian cancer cells in non-adherent culture conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Martina Battaglia,Alessandro Sacco,Eleonora Vecchio,Stefania Scicchitano,Lavinia Petriaggi,Emanuele Giorgio,Stefania Bulotta,Sonia Levi,Concetta Maria Faniello,Flavia Biamonte,Francesco Costanzo

Nanomaterials (Basel, Switzerland) 12: PubMed36432281

2022

Bacterial Magnetosomes Release Iron Ions and Induce Regulation of Iron Homeostasis in Endothelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Wenjia Lai,Dan Li,Qingsong Wang,Yan Ma,Jiesheng Tian,Qiaojun Fang

Evidence-based complementary and alternative medicine : eCAM 2022:6177477 PubMed36276874

2022

Simvastatin Inhibits Endometrial Cancer Malignant Behaviors by Suppressing RAS/Mitogen-Activated Protein Kinase (MAPK) Pathway-Mediated Reactive Oxygen Species (ROS) and Ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Zhou,Qiuhua Wu,Huajuan Qiu,Mi Li,Yanqin Ji

Frontiers in pharmacology 13:973611 PubMed36105203

2022

S-3'-hydroxy-7', 2', 4'-trimethoxyisoxane, a novel ferroptosis inducer, promotes NSCLC cell death through inhibiting Nrf2/HO-1 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Chen,Songlin Zhou,Xian Zhang,Huange Zhao

Cell death and differentiation 30:69-81 PubMed35933500

2022

Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Yao,Jingjie Peng,Endong Zhang,Dan Ji,Zhaolin Gao,Yixiong Tang,Xueyan Yao,Xiaobo Xia

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Ferroportin antibody

Western blot - Anti-Ferroportin antibody (AB235166)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

Primary Antibodies

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (7)

Product promise