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AB169577

Anti-SNIP1 antibody

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(2 제품이 사용된 논문 )

Mouse Polyclonal SNIP1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SNIP1.

대체 명칭 보기

Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1, SNIP1

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-SNIP1 antibody (AB169577)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-SNIP1 antibody (AB169577)

Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, labeling SNIP1 using ab169577 at 10 µg/ml.

주요 정보

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SNIP1.

Q8TAD8

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대체품

Primary Antibodies

AB126194

Anti-SNIP1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNIP1 antibody (AB126194)

  • 0
  • 0

보완 제품

Primary Antibodies

AB50887

Anti-Twist antibody [Twist2C1a]

Immunocytochemistry - Anti-Twist antibody [Twist2C1a] (AB50887)

  • 4
  • 27
Primary Antibodies

AB4729

Anti-Histone H3 (acetyl K27) antibody - ChIP Grade

BOND RX™ Validated

ChIP - Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (AB4729)

  • 5
  • 85
Primary Antibodies

AB281588

Anti-MAP2 antibody [RM1010] - Neuronal Marker

RabMAb|Recombinant|Lab Essentials|20ul selling size

Flow Cytometry (Intracellular) - Anti-MAP2 antibody [RM1010] - Neuronal Marker (AB281588)

  • 0
  • 0
Primary Antibodies

AB196868

Anti-FOXG1 antibody [EPR18987]

20ul selling size|RabMAb|Recombinant|Advanced Validation

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXG1 antibody [EPR18987] (AB196868)

  • 4
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

SNIP1 also known as Smad nuclear interacting protein 1 is a nuclear protein with a mass of approximately 43 kDa. This protein mechanically functions as a nuclear co-repressor that interacts with Smad proteins and the transcription factor c-Myc. SNIP1 is expressed in various tissues notably in embryonic and adult brain tissues which indicates a role in development and cellular regulation within these areas.
Biological function summary

SNIP1 influences transcriptional repression by modulating the transcriptional activity of the Smad4 complex. SNIP1 interacts with several regulatory proteins to modulate gene expression. By inhibiting the transcriptional activity of Smad proteins SNIP1 can regulate various genes involved in cell growth and proliferation affecting how cells behave in different contexts.

Pathways

SNIP1 participates in important cellular signaling pathways such as the TGF-beta and BMP signaling pathways. SNIP1 interacts with proteins in these pathways including Smad2 and Smad3 to control cellular responses to growth factors. By influencing these pathways SNIP1 plays a part in cellular processes like apoptosis and differentiation.

SNIP1 has implications in cancer and neurodevelopmental disorders. In cancer SNIP1's interaction with proteins like c-Myc and Smad3 plays a role in tumor progression highlighting its involvement in oncogenic pathways. In neurodevelopmental disorders altered SNIP1 expression affects normal brain development suggesting links between its expression and conditions such as autism spectrum disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Required for pre-mRNA splicing as component of the spliceosome (PubMed : 29360106). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
See full target information SNIP1
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell death and differentiation 30:2213-2230 PubMed37726400

2023

LncRNA BCAN-AS1 stabilizes c-Myc via N-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Guandi Wu,Jiachun Su,Lingxing Zeng,Shuang Deng,Xudong Huang,Ying Ye,Rui Li,Ruihong Bai,Lisha Zhuang,Mei Li,Quanbo Zhou,Yanfen Zheng,Junge Deng,Shaoping Zhang,Rufu Chen,Dongxin Lin,Jialiang Zhang,Jian Zheng

Journal of neuropathology and experimental neurology 77:608-627 PubMed29788265

2018

Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP.

Applications

Unspecified application

Species

Unspecified reactive species

Pol Andrés-Benito,Ellen Gelpi,Mónica Povedano,Gabriel Santpere,Isidro Ferrer
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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