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AB317169

Anti-SNRK antibody [HL2225]

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Rabbit Recombinant Monoclonal SNRK antibody. Suitable for WB and reacts with Human, Rat samples. Immunogen corresponding to Recombinant Fragment Protein within Human SNRK.

대체 명칭 보기

KIAA0096, SNFRK, SNRK, SNF-related serine/threonine-protein kinase, SNF1-related kinase

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

HL2225

Isotype

IgG

Carrier free

No

Reacts with

Human, Rat

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human SNRK.

Q9NRH2

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

제품 세부 정보

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

특성 및 보관 정보

제형
Liquid
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

SNRK also known as SNF-related kinase is a serine/threonine protein kinase with a molecular mass of approximately 80 kDa. It is part of the AMPK-related kinases family. This kinase is expressed in a wide range of tissues including heart muscle and adipose tissue. SNRK plays a role in various cellular processes by phosphorylating target proteins influencing their activity and function in the cell.
Biological function summary

Through phosphorylation SNRK controls energy balance and cellular stress responses. It does not function as part of a large protein complex but can interact with other proteins to modulate metabolic processes. SNRK contributes to regulating cell growth apoptosis and metabolism. It has a significant role in maintaining energy homeostasis and responding to nutrient availability potentially affecting metabolic syndrome.

Pathways

SNRK participates in energy-sensing pathways. It plays an important role alongside AMP-activated protein kinase (AMPK) involved in response to cellular energy levels. SNRK is also linked to the insulin signaling pathway which regulates glucose metabolism. Its activity impacts downstream targets such as acetyl-CoA carboxylase an important enzyme related to fatty acid metabolism. This indicates SNRK's importance in pathways influencing metabolic health and organism energy status.

SNRK has shown connections to metabolic disorders and cardiovascular diseases. It emerges as a potential player in the development of type 2 diabetes which involves disrupted energy regulation. Similarly in cardiovascular diseases SNRK interacts with proteins such as AMP-activated protein kinase highlighting its role in cardiac function and health. Understanding SNRK's regulation might offer insights into therapeutic strategies for these conditions.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
See full target information SNRK

Product promise

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