AB39327

Anti-SOAT 1/ACAT1 antibody

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(17 제품이 사용된 논문 )

Rabbit Polyclonal SOAT 1/ACAT1 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 17 publications.

1 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOAT 1/ACAT1 antibody (AB39327)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOAT 1/ACAT1 antibody (AB39327)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human adreanal tissue using ab39327 at 1/200 after heat induced antigen reteval in pH 6.0 citrate buffer. DAB staining.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat, Human

Applications

IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed : 16154994, PubMed : 16647063, PubMed : 32433613, PubMed : 32433614, PubMed : 32944968, PubMed : 9020103). Plays a role in lipoprotein assembly and dietary cholesterol absorption (PubMed : 16154994, PubMed : 9020103). Preferentially utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) as a substrate : shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions (PubMed : 11294643, PubMed : 32433614).

See full target information SOAT1

대체 명칭 보기

ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT, SOAT1, Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, Cholesterol acyltransferase 1, ACAT-1

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제품이 사용된 논문 (17)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Oncology letters 25:231 PubMed37153054

2023

Evaluation of sterol‑o‑acyl transferase 1 and cholesterol ester levels in plasma, peritoneal fluid and tumor tissue of patients with endometrial cancer: A pilot study.

Applications

Unspecified application

Species

Unspecified reactive species

Vijayalakshmi N Ayyagari,Miao Li,Paula Diaz-Sylvester,Kathleen Groesch,Teresa Wilson,Zvi Pasman,Ejaz M Shah,Andrea Braundmeier-Fleming,Laurent Brard

BMC cancer 22:387 PubMed35399074

2022

Assessment of the diagnostic and prognostic relevance of ACAT1 and CE levels in plasma, peritoneal fluid and tumor tissue of epithelial ovarian cancer patients - a pilot study.

Applications

Unspecified application

Species

Unspecified reactive species

Vijayalakshmi Ayyagari,Maio Li,Zvi Pasman,Xinjia Wang,Somaja Louis,Paula Diaz-Sylvester,Kathleen Groesch,Teresa Wilson,Laurent Brard

Aging 14:2678-2694 PubMed35354120

2022

piRNA-6426 increases DNMT3B-mediated SOAT1 methylation and improves heart failure.

Applications

Unspecified application

Species

Unspecified reactive species

Nier Zhong,Xiting Nong,Jiayu Diao,Guang Yang

International journal of molecular sciences 23: PubMed35409086

2022

SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?

Applications

Unspecified application

Species

Unspecified reactive species

Mario Löhr,Wolfgang Härtig,Almut Schulze,Matthias Kroiß,Silviu Sbiera,Constantin Lapa,Bianca Mages,Sabrina Strobel,Jennifer Elisabeth Hundt,Simone Bohnert,Stefan Kircher,Sudha Janaki-Raman,Camelia-Maria Monoranu

Frontiers in pharmacology 12:769647 PubMed34790132

2021

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Tingting Zhu,Zhangding Wang,Tianhui Zou,Lei Xu,Shu Zhang,Yali Chen,Chen Chen,Weijie Zhang,Shouyu Wang,Qingqing Ding,Guifang Xu

Prostate cancer and prostatic diseases 25:484-490 PubMed34326474

2021

High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Carolin Eckhardt,Iuliu Sbiera,Markus Krebs,Silviu Sbiera,Martin Spahn,Burkhard Kneitz,Steven Joniau,Martin Fassnacht,Hubert Kübler,Isabel Weigand,Matthias Kroiss

iScience 24:102722 PubMed34258555

2021

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyu Li,Woonghee Kim,Kajetan Juszczak,Muhammad Arif,Yusuke Sato,Haruki Kume,Seishi Ogawa,Hasan Turkez,Jan Boren,Jens Nielsen,Mathias Uhlen,Cheng Zhang,Adil Mardinoglu

The Journal of clinical endocrinology and metabolism 105: PubMed32449514

2020

Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.

Applications

Unspecified application

Species

Unspecified reactive species

Isabel Weigand,Barbara Altieri,Amanda M F Lacombe,Vittoria Basile,Stefan Kircher,Laura-Sophie Landwehr,Jochen Schreiner,Maria C N Zerbini,Cristina L Ronchi,Felix Megerle,Alfredo Berruti,Letizia Canu,Marco Volante,Isabel Paiva,Silvia Della Casa,Silviu Sbiera,Martin Fassnacht,Maria Candida B V Fragoso,Massimo Terzolo,Matthias Kroiss

Lipids 55:309-327 PubMed32314395

2020

High Glucose and Liver Fatty Acid Binding Protein Gene Ablation Differentially Impact Whole Body and Liver Phenotype in High-Fat Pair-Fed Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Gregory G Martin,Danilo Landrock,Avery L McIntosh,Sherrelle Milligan,Kerstin K Landrock,Ann B Kier,John Mackie,Friedhelm Schroeder

Cancers 12: PubMed31963898

2020

Sterol O-Acyl Transferase 1 as a Prognostic Marker of Adrenocortical Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Amanda Meneses Ferreira Lacombe,Iberê Cauduro Soares,Beatriz Marinho de Paula Mariani,Mirian Yumie Nishi,João Evangelista Bezerra-Neto,Helaine da Silva Charchar,Vania Balderrama Brondani,Fabio Tanno,Victor Srougi,José Luiz Chambo,Ricardo Miguel Costa de Freitas,Berenice Bilharinho Mendonca,Ana O Hoff,Madson Q Almeida,Isabel Weigand,Matthias Kroiss,Maria Claudia Nogueira Zerbini,Maria Candida Barisson Villares Fragoso

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SOAT 1/ACAT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOAT 1/ACAT1 antibody (AB39327)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Assay Kits

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (17)

Product promise