AB27469

Anti-SRD5A2 antibody

Name: Anti-SRD5A2 antibody
Brand: Abcam Limited
SKU: AB27469
Rating: 4 (1 reviews)

(1 리뷰)

(6 제품이 사용된 논문 )

Goat Polyclonal SRD5A2 antibody. Suitable for WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human SRD5A2 aa 1-50.

대체 명칭 보기

3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR type 2, Steroid 5-alpha-reductase 2, Type II 5-alpha reductase, S5AR 2, SRD5A2

1 이미지

Unknown

Western blot - Anti-SRD5A2 antibody (AB27469)

Primary incubation was 1 hour. Detected by chemiluminescence.

All lanes:

Western blot - Anti-SRD5A2 antibody (ab27469) at 0.3 µg/mL

All lanes:

Human testes lysate (35ug protein in RIPA buffer)

Predicted band size: 28 kDa

Observed band size: 26 kDa

false

주요 정보

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human SRD5A2 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P31213

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.3-1 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

보관 버퍼

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

See full target information SRD5A2

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell stem cell 27:876-889.e12 PubMed33232663

2020

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men.

Applications

Unspecified application

Species

Unspecified reactive species

Ryan M Samuel,Homa Majd,Mikayla N Richter,Zaniar Ghazizadeh,Seyedeh Maryam Zekavat,Albertas Navickas,Jonathan T Ramirez,Hosseinali Asgharian,Camille R Simoneau,Luke R Bonser,Kyung Duk Koh,Miguel Garcia-Knight,Michel Tassetto,Sara Sunshine,Sina Farahvashi,Ali Kalantari,Wei Liu,Raul Andino,Hongyu Zhao,Pradeep Natarajan,David J Erle,Melanie Ott,Hani Goodarzi,Faranak Fattahi

Oncology reports 41:1275-1283 PubMed30483800

2018

Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells.

Applications

Unspecified application

Species

Unspecified reactive species

D Herrera,O Orellana-Serradell,P Villar,M J Torres,R Paciucci,E A Castellón,H R Contreras

Developmental neuroscience 37:533-45 PubMed26279160

2015

Prenatal Stress Alters Hippocampal Neuroglia and Increases Anxiety in Childhood.

Applications

Unspecified application

Species

Unspecified reactive species

Greer A Bennett,Hannah K Palliser,Julia C Shaw,David Walker,Jonathan J Hirst

Reproductive sciences (Thousand Oaks, Calif.) 20:1365-75 PubMed23585339

2013

Changes in neuroactive steroid concentrations after preterm delivery in the Guinea pig.

Applications

Unspecified application

Species

Unspecified reactive species

Meredith A Kelleher,Jonathan J Hirst,Hannah K Palliser

The Journal of endocrinology 208:301-9 PubMed21149437

2010

Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development.

Applications

Unspecified application

Species

Unspecified reactive species

Meredith A Kelleher,Hannah K Palliser,David W Walker,Jonathan J Hirst

Reproduction, fertility, and development 21:599-607 PubMed19383266

2009

Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure.

Applications

Species

Human

Thi T Vu,Jonathan J Hirst,Michael Stark,Ian M R Wright,Hannah K Palliser,Nicolette Hodyl,Vicki L Clifton

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-SRD5A2 antibody

Western blot - Anti-SRD5A2 antibody (AB27469)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (6)

Product promise