JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB237759

Anti-STK33 antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal STK33 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human Serine/threonine-protein kinase 33 aa 200 to C-terminus.

대체 명칭 보기

Serine/threonine-protein kinase 33, STK33

2 이미지
Immunocytochemistry/ Immunofluorescence - Anti-STK33 antibody (AB237759)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-STK33 antibody (AB237759)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for STK33 (green) using ab237759 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK33 antibody (AB237759)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK33 antibody (AB237759)

Paraffin-embedded human kidney tissue stained for STK33 with ab237759 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human Serine/threonine-protein kinase 33 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9BYT3

style
left-column

대체품

Primary Antibodies

AB206296

Anti-STK33 antibody [EPR15343]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-STK33 antibody [EPR15343] (AB206296)

  • 0
  • 0

보완 제품

Primary Antibodies

AB123491

Anti-BRCA2 antibody

Immunoprecipitation - Anti-BRCA2 antibody (AB123491)

  • 4
  • 3
Proteins & Peptides

AB271749

Recombinant human STK33 protein (Active) (GST tag N-Terminus)

Functional Studies - Recombinant human STK33 protein (Active) (GST tag N-Terminus) (AB271749)

  • 0
  • 0
Primary Antibodies

AB109268

Anti-mTOR (phospho S2448) antibody [EPR426(2)]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Frozen sections) - Anti-mTOR (phospho S2448) antibody [EPR426(2)] (AB109268)

  • 4
  • 6
Primary Antibodies

AB108629

Anti-TUBA1B antibody [EPR1333] - Loading Control

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials

Flow Cytometry (Intracellular) - Anti-TUBA1B antibody [EPR1333] - Loading Control (AB108629)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity greater than 95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

STK33 also known as serine/threonine kinase 33 is a nucleic protein kinase with a mass of approximately 59 kDa. The STK33 protein functions by phosphorylating serine and threonine amino acid residues which helps to regulate various cellular processes. It is broadly expressed in different tissues such as the brain lung and liver indicating its widespread importance in cellular functions.
Biological function summary

STK33 plays a role in cell proliferation and survival. While not part of any well-defined complex STK33 affects pathways associated with tumorigenic processes. It supports cellular growth by promoting cell cycle progression and inhibiting apoptosis which can lead to increased cell proliferation. These functions highlight its potential involvement in oncogenic events where dysregulation of cell growth is a common feature.

Pathways

STK33 is involved in the PI3K/AKT signaling pathway an important pathway for cell survival and metabolism. In this context STK33 interacts with proteins such as AKT and mTOR which are key components of the pathway. Additionally STK33 has connections with the MAPK/ERK pathway linking it with proteins like MEK and ERK well-known for their roles in cell proliferation and differentiation.

STK33 frequently associates with various types of cancer including lung and pancreatic cancer. Its role in promoting cell cycle progression and inhibiting apoptosis associates it with tumor survival and growth. In cancer STK33 activity connects with oncogenic proteins like KRAS influencing cancer cell metabolism and proliferation. Understanding STK33's involvement in these pathways and diseases may offer new avenues for targeted therapeutic interventions.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Serine/threonine protein kinase required for spermatid differentiation and male fertility (PubMed : 37146716, PubMed : 38781365). Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 and AKAP4 (By similarity). Also phosphorylates vimentin/VIM, thereby regulating the dynamic behavior of the intermediate filament cytoskeleton (By similarity).
See full target information Serine/threonine-protein kinase 33
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in oncology 11:756779 PubMed34745992

2021

Androgen Receptors Act as a Tumor Suppressor Gene to Suppress Hepatocellular Carcinoma Cells Progression miR-122-5p/RABL6 Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Neng Tang,Xiaolin Dou,Xing You,Yixiong Li,Xi Li,Guodong Liu
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com