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AB235304

Anti-STK38L/Ndr2 antibody

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Rabbit Polyclonal STK38L/Ndr2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human STK38L aa 200 to C-terminus.

대체 명칭 보기

KIAA0965, NDR2, STK38L, Serine/threonine-protein kinase 38-like, NDR2 protein kinase, Nuclear Dbf2-related kinase 2

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)

Paraffin-embedded human breast cancer tissue stained for STK38L/Ndr2 using ab235304 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)

Paraffin-embedded human thymus tissue stained for STK38L/Ndr2 using ab235304 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK38L/Ndr2 antibody (AB235304)

Paraffin-embedded human ovarian cancer tissue stained for STK38L/Ndr2 using ab235304 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human STK38L aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9Y2H1

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대체품

Primary Antibodies

AB126106

Anti-STK38L/Ndr2 antibody

Western blot - Anti-STK38L/Ndr2 antibody (AB126106)

  • 0
  • 0
Primary Antibodies

AB84873

Anti-STK38L/Ndr2 antibody [3563C2a]

  • 0
  • 0

보완 제품

Primary Antibodies

AB229327

Anti-LC3B antibody - N-terminal

Lab Essentials

Flow Cytometry - Anti-LC3B antibody - N-terminal (AB229327)

  • 0
  • 0
Proteins & Peptides

AB125530

Recombinant human STK38L/Ndr2 protein (GST tag N-Terminus)

Functional Studies - Recombinant human STK38L/Ndr2 protein (AB125530)

  • 0
  • 0
Primary Antibodies

AB207612

Anti-Beclin 1 antibody [EPR19662]

20ul selling size|KO Validated|RabMAb|Recombinant|Trial Size

Immunoprecipitation - Anti-Beclin 1 antibody [EPR19662] (AB207612)

  • 5
  • 10
Primary Antibodies

AB219413

Anti-MyD88 antibody [EPR21824]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunoprecipitation - Anti-MyD88 antibody [EPR21824] (AB219413)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

STK38L also known as Ndr2 is a member of the serine/threonine kinase family and shares similarities with other Ndr family members. This protein plays a significant mechanical role in several cellular processes including regulation of cell growth and cell division. STK38L has a molecular mass of approximately 54 kDa. Researchers have observed its expression in various human tissues such as liver kidney and heart indicating its widespread functional roles in the body.
Biological function summary

STK38L acts as an important regulator by coordinating cell cycle-related activities and influences apoptosis. It is known to participate as part of the larger signaling complex interacting with scaffold proteins to ensure proper cell function. The protein mediates these biological processes through phosphorylation impacting various signaling networks and helping cells respond to different physiological conditions effectively.

Pathways

STK38L integrates into key signaling pathways such as the Hippo pathway which is essential for controlling organ size through the regulation of cell proliferation and apoptosis. This pathway involves other proteins like MST1/2 and LATS1/2 which closely interact with STK38L to maintain cellular homeostasis. The interaction with these proteins illustrates STK38L's critical positioning in cellular communication networks affecting the pathway's outcome on cellular behavior.

STK38L is associated with certain cancers and neurodegenerative disorders. Aberrant function or regulation of STK38L may contribute to the development of conditions such as hepatocellular carcinoma and Alzheimer's disease. BRCA1 and Tau proteins are related to these diseases where STK38L's interaction with or regulation of these proteins can influence disease progression providing potential therapeutic targets for intervention.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in the regulation of structural processes in differentiating and mature neuronal cells.
See full target information STK38L
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

American journal of cancer research 13:1363-1376 PubMed37168348

2023

EBNA2 mediates lipid metabolism and tumorigenesis through activation of ATF4 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Feng,Ping Zhang,Paul Yao,Hongyu Zhang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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