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AB111567

Anti-STRBP antibody

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(1 리뷰)

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(2 제품이 사용된 논문 )

Rabbit Polyclonal STRBP antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human STRBP aa 1-200.

대체 명칭 보기

SPNR, STRBP, Spermatid perinuclear RNA-binding protein

1 이미지
Western blot - Anti-STRBP antibody (AB111567)
  • WB

Unknown

Western blot - Anti-STRBP antibody (AB111567)

7.5% SDS-PAGE.

All lanes:

Western blot - Anti-STRBP antibody (ab111567) at 1/1000 dilution

All lanes:

IMR32 whole cell lysate at 30 µg/mL

Predicted band size: 74 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human STRBP aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q96SI9

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대체품

Primary Antibodies

AB237682

Anti-STRBP antibody

Immunocytochemistry/ Immunofluorescence - Anti-STRBP antibody (AB237682)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

STRBP also referred to as Spermatid Perinuclear RNA Binding Protein is a protein with a molecular mass of approximately 75 kDa. STRBP binds to RNA and has been identified as having a role in the regulation of RNA metabolism. The protein shows enriched expression in the testis suggesting a role in spermatogenesis. STRBP also contains distinct RNA-binding domains which help in its interactions with various RNA molecules in the cellular environment.
Biological function summary

STRBP participates in processes linked to RNA stabilization and processing. It acts in the formation of ribonucleoprotein complexes within the cell interacting with specific RNA substrates to influence their structure and function. The protein's localization in the testis hints at its involvement in the development or function of sperm cells. Evidence suggests that STRBP contributes to post-transcriptional regulation impacting gene expression at the RNA level.

Pathways

STRBP integrates into pathways associated with RNA processing and regulation. It plays a role in the spermatogenesis pathway where it interacts with proteins like DDX4 also known as VASA a known component of the germ cell development process. STRBP's activity in these pathways is important for understanding RNA dynamics during the progression of spermatogenesis and the maintenance of germ cell integrity.

STRBP has been studied concerning its potential link to male infertility. Alterations or abnormal expression patterns of STRBP may disrupt normal spermatogenesis potentially leading to infertility issues. Additionally connections have been proposed between STRBP and another protein YBX3 known to impact RNA stability which may also contribute to reproductive dysfunctions when dysregulated. Further studies continue to elucidate STRBP's involvement in these health conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I : C) RNA than to poly(dI : dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity).
See full target information STRBP
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of biological sciences 18:4963-4983 PubMed35982909

2022

Human promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yanqun Zhang,Shenying Ji,Xiangyu Zhang,Mengyun Lu,Yihong Hu,Yucheng Han,Guanghou Shui,Sin Man Lam,Xianqiong Zou

Cell reports 31:107656 PubMed32433965

2020

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

Applications

Unspecified application

Species

Unspecified reactive species

Emily C Freund,Anne L Sapiro,Qin Li,Sandra Linder,James J Moresco,John R Yates,Jin Billy Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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