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AB327135

Anti-TCF7L2 Antibody [CL11547]

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Mouse Monoclonal TCF-4/TCF7L2 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human TCF7L2.

대체 명칭 보기

TCF4, TCF7L2, Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, hTCF-4

5 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)

Immunohistochemical staining of human pancreas using ab327135 at 1 : 200–1 : 500 dilution, showing no nuclear positivity in exocrine glandular cells and islets of Langhernas.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)

Immunohistochemical staining of human lymph node using ab327135 at 1 : 200–1 : 500 dilution, showing very weak nuclear positivity in non-germinal center cells.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)

Immunohistochemical staining of human rectum using ab327135 at 1 : 200–1 : 500 dilution, showing moderate nuclear positivity in glandular cells.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCF7L2 Antibody [CL11547] (AB327135)

Immunohistochemical staining of mouse thalamus using ab327135 at 1 : 200–1 : 500 dilution, showing strong nuclear positivity in neuronal cells.

Western blot - Anti-TCF7L2 Antibody [CL11547] (AB327135)
  • WB

Supplier Data

Western blot - Anti-TCF7L2 Antibody [CL11547] (AB327135)

Western blot analysis in human cell line CAPAN-2 using ab327135 at 1 µg/ml.

All lanes:

Western blot - Anti-TCF7L2 Antibody [CL11547] (ab327135)

All lanes:

Human cell line CAPAN-2

Predicted band size: 67.92 kDa

false

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

CL11547

Isotype

IgG1

Carrier free

No

Reacts with

Human, Mouse

Applications

IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human TCF7L2.

Q9NQB0

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as a repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
See full target information TCF7L2
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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