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AB235781

Anti-TCTA antibody

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Rabbit Polyclonal TCTA antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TCTA aa 50 to C-terminus.

대체 명칭 보기

T-cell leukemia translocation-altered gene protein, T-cell leukemia translocation-associated gene protein, TCTA

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCTA antibody (AB235781)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCTA antibody (AB235781)

Paraffin-embedded human colon cancer tissue stained for TCTA using ab235781 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCTA antibody (AB235781)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCTA antibody (AB235781)

Paraffin-embedded human adrenal gland tissue stained for TCTA using ab235781 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human TCTA aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P57738

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보완 제품

Primary Antibodies

AB13579

Anti-TRF2 antibody [4A794]

Flow Cytometry (Intracellular) - Anti-TRF2 antibody [4A794] (AB13579)

  • 5
  • 1
Primary Antibodies

AB216343

Anti-CD38 antibody [EPR21079]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD38 antibody [EPR21079] (AB216343)

  • 5
  • 2
Primary Antibodies

AB192629

Anti-TRF1 antibody [572C]

Immunocytochemistry/ Immunofluorescence - Anti-TRF1 antibody [572C] (AB192629)

  • 3
  • 2
Primary Antibodies

AB154869

Anti-APOL3 antibody [EPR8238(2)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOL3 antibody [EPR8238(2)] (AB154869)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

T-cell leukemia translocation-associated gene (TCTA) also known as transcription factor GC-box binding protein 2 (GC-BP2) serves in different cellular processes. It has a molecular mass of approximately 29 kDa. Researchers frequently identify TCTA in various tissues but find high expression levels in lymphoid tissues particularly in T-cells. This protein interacts directly with DNA and other nuclear components to facilitate transcriptional regulation and response to cellular signals.
Biological function summary

TCTA acts as a regulatory protein involved in transcription modulation. It forms part of a transcriptional complex that affects gene expression linked to cell cycle control and immune responses. TCTA performs functions in cellular differentiation particularly in hematopoietic cells. Scientists believe it plays a role in establishing appropriate cellular states in response to external cues.

Pathways

TCTA integrates into the NF-kB signaling pathway and the JAK-STAT signaling pathway. These pathways support key processes like inflammation and immune system response. TCTA interacts with proteins such as NF-kB p65 and STAT3 influencing cellular outcomes like proliferation and apoptosis. Researchers consider TCTA's involvement important in maintaining normal function within these pathways ensuring balanced cellular activities.

TCTA has connections to several malignancies including T-cell acute lymphoblastic leukemia. It exhibits alterations that may contribute to malignancy progression by misregulating gene expression. Furthermore researchers find links between TCTA and autoimmune diseases where abnormal TCTA function might lead to inappropriate immune activation. In these contexts it often associates with abnormalities in the expression or function of proteins such as c-Myc or STAT3 highlighting its importance in disease developments and potential therapeutic targeting.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May be required for cellular fusion during osteoclastogenesis.
See full target information TCTA
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

OncoTargets and therapy 14:3721-3728 PubMed34140780

2021

G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yunfen Li,Zhengting Chen,Ke Cao,Lan Zhang,Yuhui Ma,Shuhui Yu,Hanyu Jin,Xiaoling Liu,Wenhui Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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