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AB215052

Anti-Teneurin-4 antibody

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Sheep Polyclonal Teneurin-4 antibody. Suitable for WB and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TENM4 aa 50-350.

대체 명칭 보기

KIAA1302, ODZ4, TNM4, TENM4, Teneurin-4, Ten-4, Protein Odd Oz/ten-m homolog 4, Tenascin-M4, Teneurin transmembrane protein 4, Ten-m4

1 이미지
Western blot - Anti-Teneurin-4 antibody (AB215052)
  • WB

Supplier Data

Western blot - Anti-Teneurin-4 antibody (AB215052)

All lanes:

Western blot - Anti-Teneurin-4 antibody (ab215052) at 1/1000 dilution

All lanes:

lysate from mouse embryonic tissue

Predicted band size: 308 kDa

false

주요 정보

Host species

Sheep

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human TENM4 aa 50-350. The exact immunogen used to generate this antibody is proprietary information.

Q6N022

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보완 제품

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Primary Antibodies

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Primary Antibodies

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Lyophilized
Reconstitution
reconstitute with PBS at 500µg/mL
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS)
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Teneurin-4 also known as TEN4 is a large transmembrane protein with a mass of approximately 300 kDa. It belongs to the teneurin family which is conserved across many species. Teneurin-4 is expressed in various tissues including the central nervous system where it appears extensively during development. It participates in cell adhesion and intercellular signaling suggesting an important role in guiding neuron connections.
Biological function summary

Teneurin-4 functions as an integral part of cellular structure and signaling. It engages in binding and signaling activities at the cellular junctions. In neurons Teneurin-4 contributes to synaptic organization influencing how neurons communicate with each other. It sometimes forms complexes with other membrane proteins and this interaction is essential for maintaining the synaptic balance.

Pathways

Teneurin-4 influences neurodevelopmental pathways and cellular adhesion processes. It interacts with the Ephrin and Notch signaling pathways which are vital for neuronal guidance and differentiation. Within these pathways Teneurin-4 works closely with other teneurins and ligands including the Eph receptor proteins which guide cellular positioning during tissue development.

Teneurin-4 links to several neurological disorders such as autism spectrum disorders and schizophrenia. Alterations in Teneurin-4 expression or function can disrupt normal neuronal patterns leading to these conditions. Studies also show interactions with other proteins like neurexins which are known to influence synaptic functions related to these disorders. Understanding Teneurin-4 in these contexts may help give insight into its potential role in disease mechanisms.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS) (PubMed : 26188006). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer (By similarity).
See full target information TENM4
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Anatomical record (Hoboken, N.J. : 2007) 302:1587-1593 PubMed30471213

2018

AIP1 Suppresses Transplant Arteriosclerosis Through Inhibition of Vascular Smooth Muscle Cell Inflammatory Response to IFNγ.

Applications

Unspecified application

Species

Unspecified reactive species

Lingfeng Qin,Wang Min,Shijie Xin
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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