Anti-THIK-1 antibody

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This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

THIK-1 contributes to maintaining the cellular ionic homeostasis by facilitating the passive movement of potassium ions across the cell membrane. This movement does not require additional energy input like ATP making THIK-1 efficient in sustaining ionic gradients. THIK-1 does not function as part of a larger complex but works independently to influence cell polarization and signaling important for neuron function and immune cell response.

Pathways

THIK-1 is involved in the neuronal signaling pathway and the immune response pathway. In neuronal signaling THIK-1 contributes to setting the resting potential affecting neuronal excitability and neurotransmission. In connection to the immune response THIK-1 influences the activation and function of immune cells. THIK-1 interacts with proteins such as TREK-1 and TASK channels which are also potassium channels involved in similar pathways showing redundancy and complementarity within potassium channel families.