Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted
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(3 제품이 사용된 논문 )
Mouse Monoclonal antibody. Suitable for IHC-P and reacts with Human, Rat, Mouse samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Thomsen-Friedenreich Antigen protein.
대체 명칭 보기
CD176, TF antigen
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (AB17785)
Human colon adenocarcinoma stained with ab17785 (prediluted)
Reactivity 정보
특성 및 보관 정보
제형
Purity
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The TF antigen plays roles in cell adhesion signal transduction and as a marker of cancer progression. It is not part of a larger protein complex but serves a significant role by participating in cellular recognition and immune response evasion. Researchers identified it as a pan-carcinoma antigen often used as a target for cancer immunotherapy due to its expression in many tumor tissues such as breast and colorectal cancers.
Pathways
TF antigen is involved in processes related to cell adhesion and immune evasion. These interactions often include pathways like the PI3K/AKT signaling pathway which contribute to cell survival and proliferation and involve proteins such as integrins and lectins. The alteration in pathways due to TF expression changes helps cancer cells migrate and grow making it an important target for analyzing tumor behavior.
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제품이 사용된 논문 (3)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Biochemistry and biophysics reports 5:313-327 PubMed28955838
2016
Applications
Unspecified application
Species
Unspecified reactive species
PloS one 9:e89026 PubMed24586486
2014
Applications
Unspecified application
Species
Mouse
International journal of cancer 132:2107-17 PubMed23055136
2012
Applications
Unspecified application
Species
Human
Product promise
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