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AB242544

Anti-TLT-1 antibody [EPR18153-110] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal TLT-1 antibody. Carrier free. Suitable for sELISA and reacts with Mouse samples.

대체 명칭 보기

Tlt1, Treml1, Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1

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Sandwich ELISA - Anti-TLT-1 antibody [EPR18153-110] - BSA and Azide free (Capture) (AB242544)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-TLT-1 antibody [EPR18153-110] - BSA and Azide free (Capture) (AB242544)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab206986).

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR18153-110

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab242544 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse TREML1. The recommended pair for sandwich ELISA is:
Capture: ab242544, Mouse TREML1 Capture Antibody (unconjugated)
Detector: ab242792, Mouse TREML1 Detector Antibody (unconjugated)
The reference range value is 1.95 - 125 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TLT-1 or TREM-like transcript 1 is a receptor expressed on platelets and megakaryocytes. Known for a mass of approximately 27 kDa TLT-1 belongs to the immunoglobulin superfamily. This receptor is a type I transmembrane protein and its expression is found mainly in the alpha-granules of resting platelets. During platelet activation TLT-1 translocates to the cell surface where it can participate in various cellular interactions.
Biological function summary

TLT-1 plays a significant role in hemostasis and inflammation. When considering its biological activity TLT-1 is not part of a larger protein complex but it can bind fibrinogen which facilitates clot formation and stability. This binding assists in the regulation of platelet aggregation and assists modulating the inflammatory response during vascular injury. Through its interactions at the molecular level TLT-1 enhances the overall efficiency of the clotting process.

Pathways

TLT-1 contributes to the hemostatic and pro-inflammatory pathways. It plays a part in the regulation of clot formation by interacting with other platelet surface proteins and fibrinogen. TLT-1 is associated with pathways such as the platelet activation pathway where it cooperates with proteins like P-selectin to modulate responses to vascular injury. Such interactions ensure that TLT-1 functions as an important component in maintaining circulatory system integrity.

TLT-1 connects to conditions such as thrombosis and sepsis. These disorders involve the dysfunction of the hemostatic and immune systems respectively. In thrombosis TLT-1 may contribute to excessive clot formation often interacting with proteins like fibrinogen in the process. During sepsis TLT-1 takes part in the inflammatory response which can exacerbate the clinical symptoms of the condition. Understanding the role of TLT-1 could aid in developing therapeutic targets aimed at modulating both coagulation and inflammation processes.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Cell surface receptor that may play a role in the innate and adaptive immune response.
See full target information Treml1
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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