AB237533

Anti-TMEM161A antibody

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Rabbit Polyclonal TMEM161A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM161A aa 1-100.

대체 명칭 보기

UNQ582/PRO1152, TMEM161A, Transmembrane protein 161A, Adaptive response to oxidative stress protein 29, AROS-29

2 이미지

Immunocytochemistry/ Immunofluorescence - Anti-TMEM161A antibody (AB237533)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-TMEM161A antibody (AB237533)

PC-3 (human prostate adenocarcinoma cell line) cells stained for TMEM161A (green) using ab237533 at a 1/100 dilution in ICC/IF. Secondary used is an Alexa-Fluor^®488-conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM161A antibody (AB237533)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM161A antibody (AB237533)

Paraffin-embedded human endometrial cancer tissue stained for TMEM161A with ab237533 at a 1/500 dilution in immunohistochemical analysis.

After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat, Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TMEM161A aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q9NX61

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/500", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein G

Purification 관련 사항

Purity greater than 95%

보관 버퍼

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TMEM161A also known as Transmembrane Protein 161A is a member of the larger transmembrane protein family. Structurally TMEM161A is characterized by multiple transmembrane domains. Its mass is approximately 55 kDa. Researchers have observed its expression in various tissues including the brain and kidney. The exact mechanical role is not fully elucidated but it is suggested to play a role in cellular communication through its membrane localization.

Biological function summary

TMEM161A contributes to cellular processes involving intercellular signaling and ion transport. Although scientists have not yet identified a specific complex that includes TMEM161A its function as a transmembrane protein implies potential involvement in forming channels or receptors. These elements are important for maintaining ionic balances and signaling pathways inside cells indicating TMEM161A as a supportive component in these processes.

Pathways

Recent findings indicate TMEM161A's potential involvement in cell signaling and transport pathways. An important pathway that features TMEM161A activity includes signal transduction where it may interact with proteins like ion channels such as voltage-gated channels. These interactions suggest TMEM161A could modulate responses to cellular environment changes linking it to broader cellular response mechanisms.

Scientists have noted potential links between TMEM161A and neurological disorders. Some studies suggest its involvement in conditions like epilepsy where abnormal ion transport plays a significant role. Alterations in TMEM161A expression might impact channel proteins such as voltage gated potassium channels which are important for maintaining action potentials in neurons potentially exacerbating these conditions. Research continues to explore TMEM161A's full role in these disorders.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis.

See full target information TMEM161A

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

OncoTargets and therapy 14:1007-1020 PubMed33603407

2021

Tandem Mass Tag-Based Proteomic Analysis of Potential Biomarkers for Hepatocellular Carcinoma Differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Wang,Qiang Li,Ge Huang,Bing-Yao Lin,Dongzi Lin,Yan Ma,Zhao Zhang,Tao Chen,Jie Zhou

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TMEM161A antibody

Immunocytochemistry/ Immunofluorescence - Anti-TMEM161A antibody (AB237533)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM161A antibody (AB237533)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise