JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB237680

Anti-TMEM174 antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal TMEM174 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human Transmembrane protein 174 aa 50-250.

대체 명칭 보기

Transmembrane protein 174, TMEM174

2 이미지
Immunocytochemistry/ Immunofluorescence - Anti-TMEM174 antibody (AB237680)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-TMEM174 antibody (AB237680)

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cells stained for TMEM174 (green) using ab237680 at 1/100 dilution in ICC/IF. Secondary antibody is Alexa Fluor® 488-congugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM174 antibody (AB237680)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM174 antibody (AB237680)

Paraffin-embedded human kidney tissue stained for TMEM174 using ab237680 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human Transmembrane protein 174 aa 50-250. The exact immunogen used to generate this antibody is proprietary information.

Q8WUU8

style
left-column

보완 제품

Assay Kits

AB238543

Methylglyoxal ELISA Kit

Competitive ELISA - Methylglyoxal ELISA Kit (AB238543)

  • 0
  • 0
Assay Kits

AB230933

Mouse Thrombin ELISA Kit

Recombinant|SimpleStep

ELISA - Mouse Thrombin ELISA Kit (AB230933)

  • 0
  • 0
Primary Antibodies

AB17199

Anti-Thrombin antibody [5G9]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thrombin antibody [5G9] (AB17199)

  • 4
  • 2
Primary Antibodies

AB5369

Anti-EIF2S1 antibody [EIF2a]

Western blot - Anti-EIF2S1 antibody [EIF2a] (AB5369)

  • 5
  • 4
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity greater than 95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TMEM174 also known as Transmembrane Protein 174 is an integral membrane protein with a mass of approximately 37 kDa. It exhibits expression in several tissues with higher levels observed in the bladder brain and kidney. Structurally TMEM174 is characterized by multiple transmembrane domains which suggests its potential role in cellular signaling or transport processes across the membrane.
Biological function summary

TMEM174 functions as part of cellular processes that involve ion transport and signal transduction. Although not a component of any well-characterized protein complex its positioning within the membrane and expression profile indicate a supportive role in maintaining cellular homeostasis and possibly in response to extracellular signals. Current studies continue to explore its comprehensive biological roles and interactions.

Pathways

Researchers have linked TMEM174 to regulation within the ion transport and cellular signaling pathways. There is evidence that TMEM174 may interact with proteins like SLC family transporters which suggests its participation in maintaining cellular ion balance. This positioning implicates TMEM174 in influencing cellular communication processes though more research is necessary to fully define its pathway roles.

Scientists are examining TMEM174's potential involvement in conditions like neurodegenerative disorders and kidney dysfunction. Correlations have been observed with proteins such as Tau in the context of neurodegeneration though the mechanisms remain not yet well understood. TMEM174's expression patterns and interactions indicate it could be a target for future therapeutic interventions highlighting the need for further study in various disease contexts.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Regulator of plasma phosphate homeostasis. Decreases serum inorganic phosphate (Pi) uptake by regulating the sodium-phosphate cotransporter SLC34A1 trafficking by PTH and FGF23 in the kidney.
See full target information Transmembrane protein 174
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancer biology & therapy 20:729-739 PubMed30915884

2019

The role of lncRNA MSC-AS1/miR-29b-3p axis-mediated CDK14 modulation in pancreatic cancer proliferation and Gemcitabine-induced apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yunpeng Sun,Pengfei Wang,Wenjun Yang,Yunfeng Shan,Qiyu Zhang,Huanhuan Wu
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com