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AB235788

Anti-TMEM71 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal TMEM71 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM71 aa 1-250.

대체 명칭 보기

Transmembrane protein 71, TMEM71

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM71 antibody (AB235788)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM71 antibody (AB235788)

Paraffin-embedded human gastric cancer tissue stained for TMEM71 using ab235788 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM71 antibody (AB235788)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM71 antibody (AB235788)

Paraffin-embedded human colon cancer tissue stained for TMEM71 using ab235788 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human TMEM71 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

Q6P5X7

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보완 제품

Primary Antibodies

AB152101

Anti-RBPMS antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RBPMS antibody (AB152101)

  • 4
  • 3
Primary Antibodies

AB181114

Anti-CPT2 antibody [EPR13626] - C-terminal

20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-CPT2 antibody [EPR13626] - C-terminal (AB181114)

  • 2
  • 1
Primary Antibodies

AB66217

Anti-ABCA1 antibody [HJ1]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCA1 antibody [HJ1] (AB66217)

  • 3
  • 3
Primary Antibodies

AB224250

Anti-OXCT1/SCOT antibody

KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OXCT1/SCOT antibody (AB224250)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TMEM71 also known as transmembrane protein 71 is an integral membrane protein with a mass of approximately 24 kDa. This protein is embedded within cellular membranes and exhibits expression across various tissues though more noticeable in the central nervous system. It contains several transmembrane domains which allow it to play a role in cellular transport and communication processes within the membrane. TMEM71's expression pattern suggests a role in maintaining cellular homeostasis.
Biological function summary

TMEM71 participates in intracellular signaling and transport processes. It does not function alone but often associates with other membrane proteins facilitating the transfer and modulation of signaling molecules across the cell membrane. Its ability to interact with different molecules points to its involvement in regulating cellular responses and maintaining equilibrium within cells.

Pathways

TMEM71's involvement spans several biological functions that include cellular signaling and transport. An important pathway it partakes in is the MAPK signaling pathway where it can interact with proteins like ERK1/2. This interaction aids in the regulation of cellular responses to external stimuli and phosphorylation events. Furthermore TMEM71 may influence calcium signaling pathways interacting with calcium-binding proteins to affect cellular contraction and neurotransmission.

TMEM71 has shown a connection to neurological disorders particularly those involving disrupted cellular signaling such as epilepsy. Abnormal expression or mutations in TMEM71 can influence the function of associated proteins such as those in the MAPK pathway which are important in neural cell communication. Additionally there is preliminary evidence linking TMEM71 to certain cancer types where its dysregulated expression might impact pathways essential for tumor progression and survival in association with proteins like MEK and RAF.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information TMEM71
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancer cell international 25:109 PubMed40119335

2025

TMEM71 is crucial for cell proliferation in lower-grade glioma and is linked to unfavorable prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Jiabao Xie,Wanli Yu,Shikai Gui,Lunshan Peng,Juexian Xiao,Haitao Luo,Zujue Cheng

OncoTargets and therapy 14:3721-3728 PubMed34140780

2021

G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yunfen Li,Zhengting Chen,Ke Cao,Lan Zhang,Yuhui Ma,Shuhui Yu,Hanyu Jin,Xiaoling Liu,Wenhui Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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