AB59862

Anti-TMPRSS13 antibody - Cytoplasmic domain

Be the first to review this product! 리뷰 제출

(6 제품이 사용된 논문 )

Rabbit Polyclonal TMPRSS13 antibody. Suitable for WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human TMPRSS13.

1 이미지

Unknown

Western blot - Anti-TMPRSS13 antibody - Cytoplasmic domain (AB59862)

All lanes:

Western blot - Anti-TMPRSS13 antibody - Cytoplasmic domain (ab59862) at 1/1000 dilution

Lane 1:

Cell media from human prostate adenocarcinoma LNCaP cells (treated with SF) at 20 µL

Lane 2:

Cell media from human prostate adenocarcinoma LNCaP cells (treated with TPA) at 20 µL

Lane 3:

Cell media from human prostate adenocarcinoma LNCaP cells (treated with IL1-alpha) at 20 µL

Predicted band size: 63 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human TMPRSS13. The exact immunogen used to generate this antibody is proprietary information.

Q9BYE2

style

left-column

style

left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates.</p>" } } }

style

left-column

style

left-column

특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 2.9% Sodium chloride

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

보관 정보

Stable for 12 months at -20°C

style

left-column

style

left-column

style

left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

타겟 정보

Serine protease (PubMed : 20977675, PubMed : 28710277, PubMed : 34562451). Cleaves the proform of PRSS8/prostasin to form the active protein (PubMed : 34562451). Cleaves the proform of HGF to form the active protein which promotes MAPK signaling (PubMed : 20977675). Promotes the formation of the stratum corneum and subsequently the epidermal barrier in embryos (By similarity).

See full target information TMPRSS13

대체 명칭 보기

MSP, TMPRSS11, TMPRSS13, Transmembrane protease serine 13, Membrane-type mosaic serine protease, Mosaic serine protease

style

left-column

제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in immunology 13:982839 PubMed36131918

2022

IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike.

Applications

Unspecified application

Species

Unspecified reactive species

Jérôme Gatineau,Charlotte Nidercorne,Aurélie Dupont,Marie-Line Puiffe,José L Cohen,Valérie Molinier-Frenkel,Florence Niedergang,Flavia Castellano

mBio 13:e0137622 PubMed35913162

2022

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease.

Applications

Unspecified application

Species

Unspecified reactive species

Annelies Stevaert,Ria Van Berwaer,Cato Mestdagh,Julie Vandeput,Els Vanstreels,Valerie Raeymaekers,Manon Laporte,Lieve Naesens

Biological chemistry 403:969-982 PubMed35796294

2022

TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region.

Applications

Unspecified application

Species

Unspecified reactive species

Carly E Martin,Andrew S Murray,Jacob R Mackinder,Kimberley E Sala-Hamrick,Michael G Flynn,Joseph G Lundgren,Fausto A Varela,Karin List

The Journal of biological chemistry 297:101227 PubMed34562451

2021

Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization.

Applications

Unspecified application

Species

Unspecified reactive species

Carly E Martin,Andrew S Murray,Kimberley E Sala-Hamrick,Jacob R Mackinder,Evan C Harrison,Joseph G Lundgren,Fausto A Varela,Karin List

Scientific reports 10:13896 PubMed32807808

2020

TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Fausto A Varela,Victoria L Foust,Thomas E Hyland,Kimberley E Sala-Hamrick,Jacob R Mackinder,Carly E Martin,Andrew S Murray,Sokol V Todi,Karin List

The Journal of biological chemistry 292:14867-14884 PubMed28710277

2017

Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.

Applications

Unspecified application

Species

Unspecified reactive species

Andrew S Murray,Fausto A Varela,Thomas E Hyland,Andrew J Schoenbeck,Jordan M White,Lauren M Tanabe,Sokol V Todi,Karin List

제품이 사용된 논문 모두 보기

style

left-column

style

left-column

style

right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TMPRSS13 antibody - Cytoplasmic domain

Western blot - Anti-TMPRSS13 antibody - Cytoplasmic domain (AB59862)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Proteins & Peptides

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

보관 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (6)

Product promise