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AB240148

Anti-Trypsinogen antibody [EPR11665(B)] - BSA and Azide free

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Rabbit Recombinant Monoclonal PRSS2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.
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Western blot - Anti-Trypsinogen antibody [EPR11665(B)] - BSA and Azide free (AB240148)
  • WB

Unknown

Western blot - Anti-Trypsinogen antibody [EPR11665(B)] - BSA and Azide free (AB240148)

This data was developed using ab166898, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-Trypsinogen antibody [EPR11665(B)] (<a href='/ko/products/primary-antibodies/trypsinogen-antibody-epr11665b-ab166898'>ab166898</a>) at 1/1000 dilution

All lanes:

Human pancreas lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP antibody at 1/2000 dilution

Predicted band size: 26 kDa

false

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11665(B)

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB102531

Trypsin Activity Assay Kit (Colorimetric)

Functional Studies - Trypsin Activity Assay Kit (Colorimetric) (AB102531)

  • 0
  • 0
Sample Prep & Detection Kits

AB188287

Cy3® Conjugation Kit (Fast) - Lightning-Link®

Fluorescence Resonance Energy Transfer - Cy3® Conjugation Kit (Fast) - Lightning-Link® (AB188287)

  • 0
  • 0
Sample Prep & Detection Kits

AB270709

5’ Feature Barcode Antibody Conjugation Kit - Lightning-Link® - Oligos 21-30

Schematic Diagram - 5’ Feature Barcode Antibody Conjugation Kit - Lightning-Link® - Oligos 21-30 (AB270709)

  • 0
  • 0
Primary Antibodies

AB76020

Anti-Sodium Potassium ATPase antibody [EP1845Y] - Plasma Membrane Loading Control

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sodium Potassium ATPase antibody [EP1845Y] - Plasma Membrane Loading Control (AB76020)

  • 5
  • 18
Sample Prep & Detection Kits

AB201795

Biotinylation Kit / Biotin Conjugation Kit (Fast, Type A) - Lightning-Link®

ELISA - Biotinylation Kit / Biotin Conjugation Kit (Fast, Type A) - Lightning-Link® (AB201795)

  • 0
  • 0
Primary Antibodies

AB255614

Anti-beta 2 Microglobulin antibody [EPR20040-45] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-beta 2 Microglobulin antibody [EPR20040-45] - BSA and Azide free (Detector) (AB255614)

  • 0
  • 0
Primary Antibodies

AB191598

Anti-RNA polymerase beta antibody [EPR18704]

RabMAb|Recombinant|20ul selling size

Immunoprecipitation - Anti-RNA polymerase beta antibody [EPR18704] (AB191598)

  • 5
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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제품 세부 정보

ab240148 is the carrier-free version of ab166898.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 - 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Trypsinogen also known as inactive trypsin is a precursor molecule that becomes active trypsin in the digestive system. It has a molecular mass of approximately 24 kDa. Secretory cells of the pancreas express trypsinogen and it is released into the small intestine as an inactive enzyme. In the small intestine enteropeptidase cleaves trypsinogen to form active trypsin which is important in digestion.
Biological function summary

Trypsinogen plays a role in converting proteins to peptides in the small intestine. It is part of the digestive system and contributes to the breakdown and absorption of proteins. Once activated to trypsin it works in tandem with other digestive enzymes like chymotrypsin and elastase. This teamwork ensures efficient digestion and absorption of nutrients.

Pathways

Trypsinogen is an important component in the digestive enzyme cascade. It plays a critical role in the proteolytic pathway which includes proteins like chymotrypsinogen and procarboxypeptidase. Activation of trypsin by enteropeptidase also promotes the activation of other zymogens thereby ensuring complete conversion of these inactive precursors to active enzymes vital for maintaining protein digestion.

An accumulation of trypsinogen can link to pancreatitis. This condition occurs when trypsinogen is prematurely activated within the pancreas leading to inflammation and tissue damage. Hereditary pancreatitis involves mutations in trypsinogen that result in increased autoactivation. Additionally cystic fibrosis can interfere with trypsinogen secretion and activation affecting pancreatic and digestive functions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

In the ileum, may be involved in defensin processing, including DEFA5.
See full target information PRSS2

대체 명칭 보기

TRY2, TRYP2, PRSS2, Trypsin-2, Anionic trypsinogen, Serine protease 2, Trypsin II
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Bio-protocol 15:e5424 PubMed40873476

2025

Assessing Human Treg Suppression at Single-Cell Resolution Using Mass Cytometry.

Applications

Unspecified application

Species

Unspecified reactive species

Jonas Nørskov Søndergaard,Janyerkye Tulyeu,David Priest,Shimon Sakaguchi,James B Wing
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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