AB166905

Anti-TTC14 antibody [EPR11143]

RabMAb
Recombinant
각 태그의 뜻

Be the first to review this product! 리뷰 제출

(1 출판물)

Rabbit Recombinant Monoclonal TTC14 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.

대체 명칭 보기

KIAA1980, UNQ5813/PRO19630, TTC14, Tetratricopeptide repeat protein 14, TPR repeat protein 14

2 이미지

Flow Cytometry (Intracellular) - Anti-TTC14 antibody [EPR11143] (AB166905)

Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-TTC14 antibody [EPR11143] (AB166905)

Intracellular flow cytometric analysis of permeabilized Jurkat cells labeling TTC14 using ab166905 at 1/100 dilution (red) or a rabbit IgG negative (green).

Unknown

Western blot - Anti-TTC14 antibody [EPR11143] (AB166905)

All lanes:

Western blot - Anti-TTC14 antibody [EPR11143] (ab166905) at 1/1000 dilution

Lane 1:

Daudi cell lysate at 10 µg

Lane 2:

Ramos cell lysate at 10 µg

Lane 3:

Jurkat cell lysate at 10 µg

Secondary

All lanes:

goat anti-rabbit HRP IgG antibody at 1/2000 dilution

Predicted band size: 88 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11143

Isotype

IgG

Carrier free

Reacts with

Human

Applications

Flow Cyt (Intra), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

style

left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/100 - 1/500", "FlowCytIntra-species-notes": "<a href='/ko/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody." } } }

style

left-column

제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

style

left-column

특성 및 보관 정보

제형

Liquid

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

style

left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TTC14 also known as tetratricopeptide repeat domain 14 is a protein with a molecular mass around 68 kDa. This protein plays an important mechanical role in cilia function by possessing tetratricopeptide repeat domains that facilitate protein-protein interactions necessary for its activity. TTC14 shows expression predominantly within tissues that require motile cilia like respiratory epithelium and reproductive tracts.

Biological function summary

TTC14 is involved in the functioning and maintenance of ciliary structures essential for cellular motility and fluid movement across various surfaces. TTC14 acts as a part of the ciliary transition zone a critical component that regulates ciliary protein import and function. This involvement implies a significant role in modifying the composition of ciliary membrane essential for its sensing and motility purposes.

Pathways

Researchers place TTC14 within ciliary assembly and maintenance pathways which involve coordination and transport mechanisms that ensure proper cilium structure and function. It also associates with the intraflagellar transport system working alongside proteins like IFT88 and IFT20 to sustain ciliary activities. Such participation indicates TTC14’s importance in maintaining ciliary integrity and function.

Malfunction or mutations in TTC14 can lead to conditions associated with ciliary dysfunction like Primary Ciliary Dyskinesia (PCD) and infertility due to impaired sperm motility. TTC14 shows interaction with other key ciliary-related proteins such as DNAH5 where abnormalities typically result in overlapping ciliary disorders. Consequently studying TTC14 contributes to understanding the molecular mechanisms underpinning these diseases.

style

left-column

style

left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

타겟 정보

See full target information TTC14

style

left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in oncology 13:1258863 PubMed37746252

2023

CEA-delta could be a biomarker of tumor phenotype, clinical stage, and chemotherapeutic response in rectal cancer with OCT4-positive cancer stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ivan David Lozada-Martinez,Maria Paz Bolaño-Romero,Lina Lambis-Anaya,Yamil Liscano,Amileth Suarez-Causado

제품이 사용된 논문 모두 보기

style

left-column

style

left-column

style

right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TTC14 antibody [EPR11143]

Flow Cytometry (Intracellular) - Anti-TTC14 antibody [EPR11143] (AB166905)

Western blot - Anti-TTC14 antibody [EPR11143] (AB166905)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise