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AB250389

Anti-TTC27 antibody [EPR13653] - BSA and Azide free

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Rabbit Recombinant Monoclonal TTC27 antibody. Carrier free. Suitable for ICC/IF, WB and reacts with Human samples.

대체 명칭 보기

Tetratricopeptide repeat protein 27, TPR repeat protein 27, TTC27

1 이미지
Western blot - Anti-TTC27 antibody [EPR13653] - BSA and Azide free (AB250389)
  • WB

Supplier Data

Western blot - Anti-TTC27 antibody [EPR13653] - BSA and Azide free (AB250389)

This data was developed using ab181162, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-TTC27 antibody [EPR13653] - BSA and Azide free (ab250389) at 1/5000 dilution

Lane 1:

HeLa cell lysate at 20 µg

Lane 2:

A673 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 97 kDa

false

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13653

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Primary Antibodies

AB181212

Anti-PREB antibody [EPR13252]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-PREB antibody [EPR13252] (AB181212)

  • 0
  • 0
Primary Antibodies

AB250456

Anti-ANP32C/PP32R1 antibody [EPR13354] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-ANP32C/PP32R1 antibody [EPR13354] - BSA and Azide free (AB250456)

  • 0
  • 0
Primary Antibodies

AB92628

Anti-Histone H3.3 (phospho S31) antibody [EPR1873]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H3.3 (phospho S31) antibody [EPR1873] (AB92628)

  • 3
  • 4
Primary Antibodies

AB181834

Anti-MRPL16 antibody [EPR14351]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPL16 antibody [EPR14351] (AB181834)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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제품 세부 정보

ab250389 is the carrier-free version of ab181162.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.2 - 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

TTC27 also known as Tetratricopeptide Repeat Protein 27 is a protein characterized by its tetratricopeptide repeat (TPR) domains. The molecular mass of TTC27 is approximately 143 kDa. It is expressed in various tissues with particularly high levels in the brain liver and testes. These TPR domains suggest that TTC27 may be involved in protein-protein interactions functioning as a scaffold for the assembly of multiprotein complexes.
Biological function summary

TTC27 plays important roles in cellular processes. It functions as a part of larger multiprotein complexes which indicates its role in maintaining cellular homeostasis and possibly influencing signaling pathways. The protein's distribution in the brain suggests its involvement in neurological functions though detailed mechanisms remain under investigation. TTC27's interaction with other proteins points towards its potential role in regulating cellular signaling and response.

Pathways

TTC27's involvement in specific signaling pathways highlights its importance in cellular communication. Recent studies have linked TTC27 to the MAPK/ERK pathway a critical pathway for cell proliferation and differentiation. It interacts with proteins such as MEK and ERK facilitating the transmission of extracellular signals to the nucleus. Additionally TTC27 may participate in the NOD-like receptor signaling pathway further influencing immune responses and inflammation processes.

TTC27's function and expression profile suggest potential links to certain conditions. Research indicates a connection between TTC27 and certain cancers where alterations in signaling pathways like MAPK/ERK could contribute to tumorigenesis. The correlation with proteins like ERK involved in cell cycle regulation highlights its role in cancer development. Furthermore TTC27's significant expression in the brain suggests possible involvement in neurological disorders drawing interest in its relationship with proteins implicated in neurodegenerative diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information TTC27
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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